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Efficacy of robot-assisted training on rehabilitation of upper limb function in stroke patients: A Systematic Review and Meta-Analysis

  • Author Footnotes
    # These authors contributed equally to this work.
    Xinwei Yang
    Footnotes
    # These authors contributed equally to this work.
    Affiliations
    School of Sports Medicine and Health, Chengdu Sport University, Chengdu, Sichuan Province, China
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  • Author Footnotes
    # These authors contributed equally to this work.
    Xiubo Shi
    Footnotes
    # These authors contributed equally to this work.
    Affiliations
    Hospital of Chengdu Office of People's Government of Tibetan Autonomous Region, Chengdu, Sichuan Province, China
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  • Author Footnotes
    # These authors contributed equally to this work.
    Xiali Xue
    Correspondence
    Corresponding Author: Xiali Xue, Institute of Sports Medicine and Health, Chengdu Sport University, No. 2 Tiyuan Road, Wuhou District, Chengdu, Sichuan Province, China, Tel.: +86 18483638915
    Footnotes
    # These authors contributed equally to this work.
    Affiliations
    Institute of Sports Medicine and Health, Chengdu Sport University, Chengdu, Sichuan Province, China
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  • Zhongyi Deng
    Affiliations
    Department of Rehabilitation Medicine, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong Province, China
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  • Author Footnotes
    # These authors contributed equally to this work.
Published:March 01, 2023DOI:https://doi.org/10.1016/j.apmr.2023.02.004

      Abstract

      Objective

      : To systematically evaluate the effect of robot-assisted training (RAT) on upper limb function recovery in stroke patients, providing the evidence-based medical basis for the clinical application of RAT.

      Data Sources

      We searched online electronic databases up to June 2022, including PubMed, The Cochrane Library, Scopus, Web of Science, EMBASE, WanFang Data, CNKI, and VIP full-text databases.

      Study selection

      Randomized controlled trials (RCTs) of the effect of RAT on upper extremity functional recovery in stroke patients.

      Data Extraction

      The Cochrane Collaboration Tool for Assessing the Risk of Bias was used to assess study quality and risk of bias.

      Data Synthesis

      Fourteen RCTs involving 1275 patients were included for review. Compared with the control group, RAT significantly improved upper limb motor function and daily living ability. The differences have statistical significance in overall differences, FMA-UE [SMD=0.69, 95%CI (0.34, 1.05), P=0.0001], MBI [SMD=0.95, 95%CI (0.75, 1.15), P< 0.00001]; while the differences in MAS, FIM and WMFT scores were not statistically significant. Subgroup analysis: Compared with the control group, the differences between FMA-UE and MBI at 4 and 12 weeks of RAT, there were statistically significant for both FMA-UE and MAS in stroke patients in the acute and chronic phases.

      Conclusion

      The present study showed that RAT can significantly enhance the upper limb motor function and activities of daily life in stroke patients undergoing upper limb rehabilitation.

      Keywords

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