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Research Objectives
To Investigate the correlation of AMPAC and MELD scores in patients with ESLD in pre
transplant phase.
Design
A single-center retrospective chart review was conducted on patients with diagnosis
of ESLD and liver cirrhosis and the following identifiers were extracted: age, gender,
BMI, MELD score, AM-PAC score from PT and OT consultation prior to transplant. All
results were recorded in excel. BMI were calculated as they were not readily available
in chart review. Body Mass Index (BMI) was calculated with the NIH standard Body Mass
Index (BMI) online calculator based on the patient's height (cm) and weight (kg).
Patients who did not complete both OT and PT consultations with documented AM-PAC
scores or does not have pre-operative diagnosis of ESLD and/or cirrhosis were excluded.
Setting
Non-profit academic medical center.
Participants
All adult patients admitted to the hospital with diagnosis of ESLD and liver cirrhosis
on 1/1/2019 to 8/13/2021 but has not undergone liver transplant.
Interventions
Physical and occupational therapy interventions which includes bed mobility, transfer,
balance and gait training, strengthening and ADLs self care training while in the
hospital setting.
Main Outcome Measures
Activity Measure for Post-Acute Care ‘6 clicks’ short forms (AM-PAC) and Model for
End Stage Liver Disease score (MELD).
Results
The relationship between MELD score and AMPAC scores were displayed in Figure 1. The
scatter plot showed the higher the MELD score, the lower the AMPAC scores. The correlation
was moderate in both physical therapy with rho = - 0.44 (p-value < 0.001) and occupational
therapy with rho = - 0.43 (p-value< 0.001).
Conclusions
A negative correlation exists between AMPAC scores and MELD scores in pre-transplant
patients with a diagnosis of ESLD and or liver cirrhosis. Therefore, the higher the
MELD score the lower the AMPAC score is. Our findings support the use of both scoring
system in pre-liver transplant patients in the inpatient hospital setting as a guide
for safe activity and exercise prescription.
Author(s) Disclosures
No conflicts of interests that would give perception of bias.
Key Words
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Copyright
© 2022 Published by Elsevier Inc.