Abstract
Objective
To investigate the efficacy of hydrodilatation with 40 mg triamcinolone acetonide
(TA) compared with the same procedure with 10 mg TA in patients with adhesive capsulitis
(AC) of the shoulders.
Design
Prospective, double-blind, randomized controlled trial with 12 weeks of follow-up.
Setting
Tertiary care rehabilitation center.
Participants
Eighty-four patients diagnosed with AC (N=84).
Interventions
Ultrasound guidance using (A) hydrodilatation with 4 mL of TA (40 mg)+4 mL 2% lidocaine
hydrochloride+12 mL normal saline or (B) hydrodilatation with 1 mL of TA (10 mg)+4
mL 2% lidocaine hydrochloride+15 mL normal saline through the posterior glenohumeral
recess.
Main Outcome Measures
Shoulder Pain and Disability Index (SPADI), visual analog scale (VAS) for pain, and
range of motion (ROM) at baseline and at 6 and 12 weeks after injection.
Results
Both groups experienced improvements in the SPADI score, VAS scores for pain, and
ROM throughout the study period. However, group-by-time interactions were not significant
for any outcome measurement at any follow-up time point. No adverse events were reported
in either group.
Conclusion
Ultrasound-guided hydrodilatation with 40 and 10 mg TA yielded similar improvements
in SPADI, VAS score, and ROM at the 12-week follow-up. Considering the potential detrimental
effects of corticosteroids on the adjacent cartilage and tendons, a low dose of TA
would be preferable for ultrasound-guided hydrodilatation for AC.
Keywords
List of abbreviations:
AC (adhesive capsulitis), ROM (range of motion), SPADI (Shoulder Pain and Disability Index), TA (triamcinolone acetonide), VAS (visual analog scale)To read this article in full you will need to make a payment
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Article info
Publication history
Published online: December 12, 2022
Accepted:
November 16,
2022
Received in revised form:
November 13,
2022
Received:
October 13,
2022
Publication stage
In Press Journal Pre-ProofFootnotes
This study was supported by a grant from (1) National Taiwan University Hospital, Bei-Hu Branch; (2) Ministry of Science and Technology (MOST 106–2314-B-002–180-MY3, 109–2314-B-002–114-MY3, and MOST 110-2314-B-075-013); and (3) Taiwan Society of Ultrasound in Medicine.
Clinical trial Trial Registration No.: NCT04364425.
Disclosures: none.
Identification
Copyright
© 2022 by the American Congress of Rehabilitation Medicine.
