Highlights
- •Equation to predict the oxygen consumption of individuals post-stroke is necessary.
- •An equation with clinical applicability and adequate validity was provided.
- •V̇o2max=22.239+0.020 × distance in the 6MWT+4.039 × sex-0.157 × age-0.265 × BMI.
- •Studies with larger sample must investigate the external validity of this equation.
Abstract
Objective
To develop an equation with clinical applicability and adequate validity to predict
the maximum oxygen consumption (V̇o2max) of individuals post-stroke.
Design
A cross-sectional study.
Setting
A university laboratory.
Participants
Individuals post-stroke in the chronic phase (at least 6 months post-stroke). Step-1
(equation development): n=50, aged 55±12 years; Step-2 (validity investigation): n=20,
aged 58±8 years (N=50 [step 1], N=20 [step 2]).
Interventions
Not applicable.
Main Outcome Measure(s)
Step-1 (equation development): multiple linear regression analysis was performed.
Dependent variable: V̇o2max (mL/kg/min) in the cardiopulmonary exercise test. Independent variables: age (years), sex
(1-women, 2-men), body mass index (BMI) (kg/m2), and distance (meters) in the Six-Minute Walk Test (6MWT) (6MWT-Equation) or in
the Incremental Shuttle Walk Test (ISWT) (ISWT-Equation). Step-2 (validity investigation):
agreement between the V̇o2max measured and predicted was evaluated with the intraclass correlation coefficient
(ICC) with 95% confidence interval (CI) and the Bland-Altman method (α=5%).
Results
In step-1 (equation development), the 4 independent variables for each equation were
retained (6MWT-Equation: R2=0.68, P<.001; ISWT-Equation: R2=0.58, P<.001). In step-2 (validity investigation), the 6MWT-Equation showed an ICC of 0.73
(95% CI=0.30, 0.89; P=.004) and a mean bias of 0.003 mL/kg/min; and the ISWT-Equation showed an imprecise
ICC of 0.55 (95% CI=-0.12, 0.82; P=.045) and a mean bias of 0.971 mL/kg/min. 6MWT-Equation (V̇o2max=22.239+0.02 × distance in the 6MWT+4.039 × sex-0.157 × age-0.265 × BMI) showed adequate
validity.
Conclusions
An equation with clinical applicability and adequate validity in the investigated
sample was developed to predict the V̇o2max of individuals post-stroke in the chronic phase (6MWT-Equation). Future studies with
larger sample should investigate its external validity.
Keywords
List of abbreviations:
BMI (body mass index), CI (confidence interval), CPET (cardiopulmonary exercise test), ICC (intraclass correlation coefficient), ISWT (Incremental Shuttle Walk Test), V̇o2max (maximum oxygen consumption), 6MWT (Six-Minute Walk Test), 10mWT (10-meter walk test)To read this article in full you will need to make a payment
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Article info
Publication history
Published online: December 06, 2022
Accepted:
November 15,
2022
Received in revised form:
November 11,
2022
Received:
April 20,
2022
Publication stage
In Press Journal Pre-ProofFootnotes
This work was supported by the (Coordenação de Aperfeiçoamento de Pessoal de Nível Superior [CAPES], grant number 001); (Fundação de Amparo à Pesquisa do Estado de Minas Gerais [FAPEMIG]); (Conselho Nacional de Desenvolvimento Científico e Tecnológico [CNPq]); and (Pró-reitoria de Pesquisa da Universidade Federal de Minas Gerais [PRPq/UFMG]).
Disclosures: none.
Identification
Copyright
© 2022 by the American Congress of Rehabilitation Medicine.
