Advertisement
ORIGINAL RESEARCH| Volume 103, ISSUE 12, P2383-2390, December 2022

Association of Function, Symptoms, and Social Support Reported in Standardized Outpatient Clinic Questionnaires With Subsequent Hospital Discharge Disposition and 30-Day Readmissions

  • Tamra Keeney
    Correspondence
    Corresponding author Tamra Keeney, DPT, PhD, Division of Palliative Care and Geriatric Medicine, Mongan Institute Center for Aging and Serious Illness, Massachusetts General Hospital, 100 Cambridge Street, Suite 1600, Boston, MA 02114.
    Affiliations
    Division of Palliative Care and Geriatric Medicine, Department of Medicine, Massachusetts General Hospital, Boston, MA

    Center for Aging and Serious Illness, Mongan Institute, Massachusetts General Hospital, Boston, MA

    Department of Health Services, Policy & Practice, Brown University, School of Public Health, Providence, RI
    Search for articles by this author
  • Minji K. Lee
    Affiliations
    Kern Center for the Science of Health Care Delivery, Mayo Clinic, Rochester, MN
    Search for articles by this author
  • Jeffrey R. Basford
    Affiliations
    Department of Physical Medicine and Rehabilitation, Mayo Clinic, Rochester, MN
    Search for articles by this author
  • Andrea Cheville
    Affiliations
    Kern Center for the Science of Health Care Delivery, Mayo Clinic, Rochester, MN

    Department of Physical Medicine and Rehabilitation, Mayo Clinic, Rochester, MN
    Search for articles by this author

      Abstract

      Objective

      To determine whether patient-reported information, routinely collected in an outpatient setting, is associated with readmission within 30 days of discharge and/or the need for post-acute care after a subsequent hospital admission.

      Design

      Retrospective cohort study. Six domains of patient-reported information collected in the outpatient setting (psychological distress, respiratory symptoms, musculoskeletal pain, family support, mobility, and activities of daily living [ADLs]) were linked to electronic health record hospitalization data. Mixed effects logistic regression models with random intercepts were used to identify the association between the 6 domains and outcomes.

      Setting

      Outpatient clinics and hospitals in a Midwestern health system.

      Participants

      7671 patients who were hospitalized 11,445 times between May 2004 and May 2014 (N=7671).

      Intervention

      None.

      Main Outcome Measures

      30-day hospital readmission and discharge home vs facility.

      Results

      Domains were significantly associated with 30-day readmission and placement in a facility. Specifically, mobility (odds ratio [OR]=1.30; 95% confidence interval [CI], 1.16, 1.46), ADLs (OR=1.27; 95% CI, 1.13, 1.42), respiratory symptoms (OR=1.26; 95% CI, 1.12, 1.41), and psychological distress (OR=1.20; 95% CI, 1.07, 1.35) had the strongest associations with 30-day readmission. The ADL (OR=2.52; 95% CI, 2.26, 2.81), mobility (OR=2.35; 95% CI, 2.10, 2.63), family support (OR=2.28; 95% CI, 1.98, 2.62), and psychological distress (OR=1.38; 95% CI, 1.25, 1.52) domains had the strongest associations with discharge to an institution.

      Conclusions

      Patient-reported function, symptoms, and social support routinely collected in outpatient clinics are associated with future 30-day readmission and discharge to an institutional setting. Whether these data can be leveraged to guide interventions to address patient needs and improve outcomes requires further research.

      Keywords

      List of abbreviations:

      ADLs (activities of daily living), CI (confidence interval), CVI (current visit information), EHR (electronic health record), MIRT (multidimensional item response theory), OR (odds ratio), PROM (patient-reported outcome measure), ROS (review of systems), SNF (skilled nursing facility)
      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'

      Subscribe:

      Subscribe to Archives of Physical Medicine and Rehabilitation
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect

      References

        • Lavallee DC
        • Chenok KE
        • Love RM
        • et al.
        Incorporating patient-reported outcomes into health care to engage patients and enhance care.
        Health Aff. 2016; 35: 575-582
        • Mahmoud AN
        • Elgendy IY
        • Mojadidi MK
        • et al.
        Prevalence, causes, and predictors of 30-day readmissions following hospitalization with acute myocardial infarction complicated by cardiogenic shock: findings from the 2013-2014 National Readmissions Database.
        J Am Heart Assoc. 2018; 7e008235
        • Shams I
        • Ajorlou S
        • Yang K.
        A predictive analytics approach to reducing 30-day avoidable readmissions among patients with heart failure, acute myocardial infarction, pneumonia, or COPD.
        Health Care Manag Sci. 2015; 18: 19-34
        • Johnston KJ
        • Wen H
        • Schootman M
        • Maddox KEJ.
        Association of patient social, cognitive, and functional risk factors with preventable hospitalizations: implications for physician value-based payment.
        J Gen Intern Med. 2019; 34: 1645-1652
        • Johnston KJ
        • Maddox KEJ.
        The role of social, cognitive, and functional risk factors in Medicare spending for dual and nondual enrollees.
        Health Aff. 2019; 38: 569-576
        • Straatmann VS
        • Dekhtyar S
        • Meinow B
        • Fratiglioni L
        • Calderon-Larranaga A.
        Unplanned hospital care use in older adults: the role of psychological and social well-being.
        J Am Geriatr Soc. 2020; 68: 272-280
        • Willers C
        • Boström AM
        • Carlsson L
        • Lager A
        • Lindqvist R
        • Rydwik E.
        Readmission within three months after inpatient geriatric care—incidence, diagnosis and associated factors in a Swedish cohort.
        PLoS One. 2021; 16e0248972
        • Teramatsu H
        • Shiraishi J
        • Matsushima Y
        • Araki M
        • Okazaki T
        • Saeki S.
        Using physical function to predict hospital readmission within 1 year in patients with heart failure.
        Prog Rehabil Med. 2019; 420190018
        • Setoguchi M
        • Hashimoto Y
        • Sasaoka T
        • Ashikaga T
        • Isobe M.
        Risk factors for rehospitalization in heart failure with preserved ejection fraction compared with reduced ejection fraction.
        Heart Vessels. 2015; 30: 595-603
        • Lu MLR
        • Venecia TAD
        • Goyal A
        • et al.
        Psychiatric conditions as predictors of rehospitalization among African American patients hospitalized with heart failure.
        Clin Cardiol. 2017; 40: 1020-1025
        • Hoyler MM
        • Abramovitz MD
        • Ma X
        • et al.
        Social determinants of health affect unplanned readmissions following acute myocardial infarction.
        J Comp Effect Res. 2020; 10: 39-54
        • Middleton A
        • Graham JE
        • Lin YL
        • et al.
        Motor and cognitive functional status are associated with 30-day unplanned rehospitalization following post-acute care in Medicare Fee-for-Service beneficiaries.
        J Gen Intern Med. 2016; 31: 1427-1434
        • Middleton A
        • Downer B
        • Haas A
        • Knox S
        • Ottenbacher KJ.
        Functional status is associated with 30-day potentially preventable readmissions following home health care.
        Med Care. 2019; 57: 145-151
        • Middleton A
        • Downer B
        • Haas A
        • Lin YL
        • Graham JE
        • Ottenbacher KJ.
        Functional status is associated with 30-day potentially preventable readmissions following skilled nursing facility discharge among Medicare beneficiaries.
        J Am Med Dir Assoc. 2018; 19: 348-354
        • Greysen SR
        • Cenzer IS
        • Auerbach AD
        • Covinsky KE.
        Functional impairment and hospital readmission in Medicare seniors.
        JAMA Intern Med. 2015; 175: 559-565
        • Soley-Bori M
        • Soria-Saucedo R
        • Ryan CM
        • et al.
        Functional status and hospital readmissions using the Medical Expenditure Panel Survey.
        J Gen Intern Med. 2015; 30: 965-972
        • Cheng Y
        • Goodin AJ
        • Pahor M
        • Manini T
        • Brown JD.
        Healthcare utilization and physical functioning in older adults in the United States.
        J Am Geriatr Soc. 2019; 68: 266-271
        • Greysen SR
        • Cenzer IS
        • Boscardin WJ
        • Covinsky KE.
        Functional impairment: an unmeasured marker of Medicare costs for postacute care of older adults.
        J Am Geriatr Soc. 2017; 65: 1996-2002
      1. Centers for Medicare and Medicaid Services (CMS). Hospital Readmissions Reduction Program (HRRP); 2020. Available at: https://www.cms.gov/Medicare/Medicare-Fee-for-Service-Payment/AcuteInpatientPPS/Readmissions-Reduction-Program. Accessed March 10, 2020.

        • Kim LK
        • Yeo I
        • Cheung JW
        • et al.
        Thirty-day readmission rates, timing, causes, and costs after ST-segment-elevation myocardial infarction in the United States: a national readmission database analysis 2010-2014.
        J Am Heart Assoc Cardiovasc Cerebrovasc Dis. 2018; 7e009863
        • Lee MK
        • Basford JR
        • Heinemann AW
        • Cheville A.
        Assessing whether ad hoc clinician-generated patient questionnaires provide psychometrically valid information.
        Health Qual Life Outcomes. 2020; 18: 50
        • Yan S
        • Kwan YH
        • Tan CS
        • Thumboo J
        • Low LL.
        A systematic review of the clinical application of data-driven population segmentation analysis.
        BMC Med Res Methodol. 2018; 18: 121
        • Ng SH
        • Rahman N
        • Ang IYH
        • et al.
        Characterization of high healthcare utilizer groups using administrative data from an electronic medical record database.
        BMC Health Serv Res. 2019; 19: 452
        • Rosella LC
        • Kornas K
        • Yao Z
        • et al.
        Predicting high health care resource utilization in a single-payer public health care system: development and validation of the high resource user population risk tool.
        Med Care. 2018; 56: e61-e69
        • Pederson JL
        • Warkentin LM
        • Majumdar SR
        • McAlister FA.
        Depressive symptoms are associated with higher rates of readmission or mortality after medical hospitalization: a systematic review and meta-analysis.
        J Hosp Med. 2016; 11: 373-380
        • Iyer AS
        • Bhatt SP
        • Garner JJ
        • et al.
        Depression is associated with readmission for acute exacerbation of chronic obstructive pulmonary disease.
        Ann Am Thorac Soc. 2016; 13: 197-203
        • Nipp RD
        • El-Jawahri A
        • Moran SM
        • et al.
        The relationship between physical and psychological symptoms and health care utilization in hospitalized patients with advanced cancer.
        Cancer. 2017; 123: 4720-4727
        • Johnson PC
        • Xiao Y
        • Wong RL
        • et al.
        Potentially avoidable hospital readmissions in patients with advanced cancer.
        J Oncol Pract. 2019; 15: e420-e427
        • Retrum JH
        • Boggs J
        • Hersh A
        • et al.
        Patient-identified factors related to heart failure readmissions.
        Circulation Cardiovasc Qual Outcomes. 2013; 6: 171-177
        • Chen J
        • Sadasivam R
        • Blok AC
        • et al.
        The association between patient-reported clinical factors and 30-day acute care utilization in chronic heart failure.
        Med Care. 2020; 58: 336-343
        • Howard-Anderson J
        • Busuttil A
        • Lonowski S
        • Vangala S
        • Afsar-Manesh N.
        From discharge to readmission: understanding the process from the patient perspective.
        J Hosp Med. 2016; 11: 407-412
        • Johnston KJ
        • Wen H
        • Kotwal A
        • Maddox KEJ.
        Comparing preventable acute care use of rural versus urban Americans: an observational study of national rates during 2008-2017.
        J Gen Intern Med. 2021; 36: 3728-3736
        • Murray F
        • Allen M
        • Clark CM
        • Daly CJ
        • Jacobs DM.
        Socio-demographic and -economic factors associated with 30-day readmission for conditions targeted by the hospital readmissions reduction program: a population-based study.
        BMC Public Health. 2021; 21: 1922
        • Werner RM
        • Coe NB
        • Qi M
        • Konetzka RT.
        Patient outcomes after hospital discharge to home with home health care vs to a skilled nursing facility.
        JAMA Intern Med. 2019; 179: 617-623
        • Kosar CM
        • Loomer L
        • Ferdows NB
        • Trivedi AN
        • Panagiotou OA
        • Rahman M.
        Assessment of rural-urban differences in postacute care utilization and outcomes among older US adults.
        JAMA Netw Open. 2020; 3e1918738
        • Porter I
        • Goncalves-Bradley D
        • Ricci-Cabello I
        • et al.
        Framework and guidance for implementing patient-reported outcomes in clinical practice: evidence, challenges and opportunities.
        J Comp Effect Res. 2016; 5: 507-519
        • Blumenthal KJ
        • Chang Y
        • Ferris TG
        • et al.
        Using a self-reported global health measure to identify patients at high risk for future healthcare utilization.
        J Gen Intern Med. 2017; 32: 877-882
        • Basch E
        • Deal AM
        • Kris MG
        • et al.
        Symptom monitoring with patient-reported outcomes during routine cancer treatment: a randomized controlled trial.
        J Clin Oncol. 2016; 34: 557-565
        • Cheville AL
        • Moynihan T
        • Herrin J
        • Loprinzi C
        • Kroenke K.
        Effect of collaborative telerehabilitation on functional impairment and pain among patients with advanced-stage cancer: a randomized clinical trial.
        JAMA Oncol. 2019; 5: 644-652
        • Hsiao CJ
        • Dymek C
        • Kim B
        • Russell B.
        Advancing the use of patient-reported outcomes in practice: understanding challenges, opportunities, and the potential of health information technology.
        Qual Life Res. 2019; 28: 1575-1583
        • Austin E
        • LeRouge C
        • Hartzler AL
        • Chung AE
        • Segal C
        • Lavallee DC.
        Opportunities and challenges to advance the use of electronic patient-reported outcomes in clinical care: a report from AMIA workshop proceedings.
        JAMA Open. 2019; 2: 407-410
        • Austin E
        • LeRouge C
        • Hartzler AL
        • Segal C
        • Lavallee DC.
        Capturing the patient voice: implementing patient-reported outcomes across the health system.
        Qual Life Res. 2020; 29: 347-355
        • Basch E
        • Barbera L
        • Kerrigan CL
        • Velikova G.
        Implementation of patient-reported outcomes in routine medical care.
        Am Soc Clin Oncol Educ Book. 2018; 38: 122-134
        • Gensheimer SG
        • Wu AW
        • Snyder CF
        PRO-EHR Users’ Guide Steering Group; PRO-EHR Users’ Guide Working Group. Oh, the places we'll go: patient-reported outcomes and electronic health records.
        Patient. 2018; 11: 591-598