We thank the authors of this Letter to the Editor for their interest in our article
and the Editors for the invitation to respond. We agree on the need for a unifying
conceptual framework and the value that this would add to guiding precision rehabilitation.
We also support the need to include patients as active collaborators and recognize
the potential role of genetics in precision medicine. However, we do wish to underscore
the importance of careful measurement and monitoring of whole-person function as the
core of precision rehabilitation. As the authors of the Letter to the Editor point
out, this must be done by capturing function that is meaningful to the patient, making
patients an essential stakeholder in the precision rehabilitation initiative.
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References
- Genome-wide association meta-analysis of functional outcome after ischemic stroke.Neurology. 2019; 92: e1271-e1283
- Precision rehabilitation: optimizing function, adding value to health care.Arch Phys Med Rehabil. 2022; 103: 1233-1239
- Genetic variation in the dopamine system influences intervention outcome in children with cerebral palsy.EBioMedicine. 2018; 28: 162-167
- Prediction, not association, paves the road to precision medicine.JAMA Psychiatry. 2021; 78: 127-128
- Neuroscience needs behavior: correcting a reductionist bias.Neuron. 2017; 93: 480-490
Article info
Publication history
Published online: June 09, 2022
Accepted:
May 18,
2022
Received:
May 18,
2022
Footnotes
Disclosures: none.
Identification
Copyright
© 2022 by the American Congress of Rehabilitation Medicine.
ScienceDirect
Access this article on ScienceDirectLinked Article
- Precision Rehabilitation: Optimizing Function, Adding Value to Health CareArchives of Physical Medicine and RehabilitationVol. 103Issue 9
- PreviewWe commend French et al1 on their excellent timely contribution to the evolving field of precision medicine with a strong focus on functional real-world outcomes. In June 2021 our National Institutes of Health Medical Rehabilitation Research Resource Network hosted a Precision Rehabilitation conference that endorsed many topics well delineated by French et al. Among these are the need for greater standardization and precision in measuring function, more frequent and longitudinal assessments, use of more varied study designs and heterogeneous patient populations, and strategic use of technology advances (electronic health records, wearable devices).
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