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Response to Letter to the Editor Regarding “Precision Rehabilitation: Optimizing Function, Adding Value to Health Care”

      We thank the authors of this Letter to the Editor for their interest in our article and the Editors for the invitation to respond. We agree on the need for a unifying conceptual framework and the value that this would add to guiding precision rehabilitation. We also support the need to include patients as active collaborators and recognize the potential role of genetics in precision medicine. However, we do wish to underscore the importance of careful measurement and monitoring of whole-person function as the core of precision rehabilitation. As the authors of the Letter to the Editor point out, this must be done by capturing function that is meaningful to the patient, making patients an essential stakeholder in the precision rehabilitation initiative.
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      References

        • Soderholm M
        • Pedersen A
        • Lorentzen E
        • et al.
        Genome-wide association meta-analysis of functional outcome after ischemic stroke.
        Neurology. 2019; 92: e1271-e1283
        • French MA
        • Roemmich RT
        • Daley K
        • et al.
        Precision rehabilitation: optimizing function, adding value to health care.
        Arch Phys Med Rehabil. 2022; 103: 1233-1239
        • Diaz Heijtz R
        • Almeida R
        • Eliasson AC
        • Forssberg H.
        Genetic variation in the dopamine system influences intervention outcome in children with cerebral palsy.
        EBioMedicine. 2018; 28: 162-167
        • Bzdok D
        • Varoquaux G
        • Steyerberg EW.
        Prediction, not association, paves the road to precision medicine.
        JAMA Psychiatry. 2021; 78: 127-128
        • Krakauer JW
        • Ghazanfar AA
        • Gomez-Marin A
        • MacIver MA
        • Poeppel D.
        Neuroscience needs behavior: correcting a reductionist bias.
        Neuron. 2017; 93: 480-490

      Linked Article

      • Response to Precision Rehabilitation: Optimizing Function, Adding Value to Health Care
        Archives of Physical Medicine and Rehabilitation
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          We commend French et al1 on their excellent timely contribution to the evolving field of precision medicine with a strong focus on functional real-world outcomes. In June 2021 our National Institutes of Health Medical Rehabilitation Research Resource Network hosted a Precision Rehabilitation conference that endorsed many topics well delineated by French et al. Among these are the need for greater standardization and precision in measuring function, more frequent and longitudinal assessments, use of more varied study designs and heterogeneous patient populations, and strategic use of technology advances (electronic health records, wearable devices).
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