We commend French et al
1
on their excellent timely contribution to the evolving field of precision medicine
with a strong focus on functional real-world outcomes. In June 2021 our National Institutes
of Health Medical Rehabilitation Research Resource Network hosted a Precision Rehabilitation
conference that endorsed many topics well delineated by French et al. Among these
are the need for greater standardization and precision in measuring function, more
frequent and longitudinal assessments, use of more varied study designs and heterogeneous
patient populations, and strategic use of technology advances (electronic health records,
wearable devices). Their emphasis on prediction, innovation in big-data analytical
approaches, and collaborative team science is commendable but seriously limited by
omitting 3 salient topics from the retreat and subsequent discussions: (1) the value
of patients as active collaborators, (2) the potential high effect of genomics and
biomarkers, and (3) the need for a unifying transdisciplinary framework to guide research
and practice. We write this letter to stimulate further dialogue and inspire innovation.To read this article in full you will need to make a payment
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References
- Precision rehabilitation: optimizing function, adding value to health care.Arch Phys Med Rehabil. 2022; 103: 1233-1239
- Developing and systematically implementing participatory action research.Arch Phys Med Rehabil. 2004; 85: 3-12
- Adapting a conceptual framework to engage diverse stakeholders in genomic/precision medicine research.Health Expect. 2022 Mar 30; ([Epub ahead of print])
- The National Academies’ roundtable on genomics and precision health: where we have been and where we are heading.Am J Hum Genet. 2021; 108: 1817-1822
- Genetic variation in the dopamine system influences intervention outcome in children with cerebral palsy.EBioMedicine. 2018; 28: 162-167
- Epigenetics and the International Classification of Functioning, Disability and Health model: bridging nature, nurture, and patient-centered population health.Phys Ther. 2022; 102: 1-11
Article info
Publication history
Published online: June 08, 2022
Accepted:
April 30,
2022
Received:
April 28,
2022
Identification
Copyright
© 2022 by the American Congress of Rehabilitation Medicine.
ScienceDirect
Access this article on ScienceDirectLinked Article
- Response to Letter to the Editor Regarding “Precision Rehabilitation: Optimizing Function, Adding Value to Health Care”Archives of Physical Medicine and RehabilitationVol. 103Issue 9
- PreviewWe thank the authors of this Letter to the Editor for their interest in our article and the Editors for the invitation to respond. We agree on the need for a unifying conceptual framework and the value that this would add to guiding precision rehabilitation. We also support the need to include patients as active collaborators and recognize the potential role of genetics in precision medicine. However, we do wish to underscore the importance of careful measurement and monitoring of whole-person function as the core of precision rehabilitation.
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