Abstract
Objective
To determine the effects of virtual reality (VR) rehabilitation training on the cognitive
function and activities of daily living (ADL) of patients with poststroke cognitive
impairment (PSCI).
Data Sources
Four Chinese databases and 6 English databases were systematically searched for studies
published until August 31, 2021, by using Medical Subject Headings of the National
Library of Medicine terms such as virtual reality, cognition disorders, cognitive
dysfunction, and stroke and free terms such as virtual environment, VR, cognition
impairment, cerebrovascular accident, and PSCI.
Study Selection
Randomized controlled trials treating PSCI with VR training were included. The control
groups received conventional treatments such as conventional rehabilitation training
and drug therapy; the experimental groups received VR rehabilitation training. The
outcome measures were cognitive function and ADL.
Data Extraction
Two researchers independently extracted key information from eligible studies. The
methodological quality of the studies was evaluated using the Cochrane Handbook for
Systematic Reviews of Interventions v5.1.0. Meta-analysis was performed using RevMan
v5.4. We followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses
2020 guidelines.
Data Synthesis
Twenty-one studies (1149 participants) were included. Meta-analyses found that compared
with the control group, VR rehabilitation training increased Mini-Mental State Examination,
Montreal Cognitive Assessment, Loewenstein Occupational Therapy Cognitive Assessment,
Rivermead Behavioral Memory Test Second Edition, Barthel Index, Modified Barthel Index,
and FIM scores; event-related potential 300 (P300) amplitude; and the N-acetylaspartate/creatinine
(Cr) ratio on proton magnetic resonance spectroscopy (1H-MRS) and reduced P300 latency; Trail Making Test scores; and the choline-containing
compounds/Cr ratio on 1H-MRS (all P<.05). These results indicated that VR training improved cognitive function and ADL
in PSCI.
Conclusions
VR rehabilitation training promotes the rehabilitation of cognitive function and recovery
of ADL in patients with PSCI and may be a good complementary approach to conventional
cognitive interventions.
Keywords
List of abbreviations:
ADL (activities of daily living), BI (Barthel Index), Cho (choline-containing compounds), Cr (creatinine), 1H-MRS (proton magnetic resonance spectroscopy), LOTCA (Loewenstein Occupational Therapy Cognitive Assessment), MBI (Modified Barthel Index), MD (mean difference), MMSE (Mini-Mental State Examination), MoCA (Montreal Cognitive Assessment), NAA (N-acetylaspartate), OR (odds ratio), PSCI (poststroke cognitive impairment), P300 (event-related potential 300), RBMT-II (Rivermead Behavioral Memory Test Second Edition), RCT (randomized controlled trial), TMT (Trail Making Test), VR (virtual reality), WAIS-III (Wechsler Adult Intelligence Scale-Ⅲ)To read this article in full you will need to make a payment
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Article info
Publication history
Published online: April 09, 2022
Accepted:
March 27,
2022
Received in revised form:
March 22,
2022
Received:
November 30,
2021
Footnotes
Supported by Special Project of Nursing at high altitude of Fujian University of Traditional Chinese Medicine (Grant No. X2021007- Discipline).
Disclosures: none
Identification
Copyright
© 2022 by the American Congress of Rehabilitation Medicine.
