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Letter to the Editor: Efficacy of Physical Exercise on Cortical Activity Modulation in Mild Cognitive Impairment: Comments on a Systematic Review

Published:February 06, 2022DOI:https://doi.org/10.1016/j.apmr.2022.01.144
      Pedroso et al
      • Pedroso R
      • Lima-Silva A
      • Tarachuque P
      • Fraga F
      • Stein A.
      Efficacy of physical exercise on cortical activity modulation in mild cognitive impairment: a systematic review.
      recently conducted a systematic review to assess the effects of physical exercise on cortical activity modulation in patients with mild cognitive impairment (MCI). The review includes 5 randomized controlled trials and 2 nonrandomized controlled trials. We have many comments on some procedures and findings in this review.
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      Linked Article

      • Response to Letter to the Editor: Efficacy of Physical Exercise on Cortical Activity Modulation in Mild Cognitive Impairment: Comments on a Systematic Review
        Archives of Physical Medicine and RehabilitationVol. 103Issue 5
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          We thank the authors for their letter to the editor related to our recent article.1 The authors expressed 4 main concerns related to our systematic review. The first is related to the absence of specification in relation to the etiology of mild cognitive impairment (MCI).2 We decided to not specify MCI etiology because (1) there are only a few studies in this area; therefore, any additional restriction could have reduced the number of included studies (n=7); and (2) the main aim of our systematic review was to provide a synthesis of the current literature investigating the effects of physical exercise on cortical activity measured via electroencephalogram in individuals with MCI, not on the MCI cause.
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