We read with great interest the study by Renner et al,
1which compared arm cycle–based unilateral and bilateral arm training in patients with stroke who have severe upper limb paresis. The study concluded that both of the interventions improved upper limb function after training, and bilateral arm training showed significant functional improvement in patients with pure subcortical stroke. To our knowledge, this is the first randomized controlled trial that investigates the relationship between lesion location and the efficacy of arm training, and we appreciate the author's contribution. However, we would like to respectfully raise a few queries regarding their findings.
- Renner CI
- Brendel C
- Hummelsheim H.
Bilateral arm training vs unilateral arm training for severely affected patients with stroke: exploratory single-blinded randomized controlled trial.
Arch Phys Med Rehabil. 2020; 101: 1120-1130
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- Bilateral arm training vs unilateral arm training for severely affected patients with stroke: exploratory single-blinded randomized controlled trial.Arch Phys Med Rehabil. 2020; 101: 1120-1130
- Transcallosal inhibition in chronic subcortical stroke.Neuroimage. 2005; 28: 940-946
- Constraint-induced movement therapy combined with transcranial direct current stimulation over premotor cortex improves motor function in severe stroke: a pilot randomized controlled trial.Rehabil Res Pract. 2017; 20176842549
- A multi-center study on low-frequency rTMS combined with intensive occupational therapy for upper limb hemiparesis in post-stroke patients.J Neuroeng Rehabil. 2012; 9: 4
- Constraint-induced movement therapy after stroke.Lancet Neurol. 2015; 14: 224-234
Published online: August 07, 2021
Accepted: May 6, 2021
Received in revised form: May 4, 2021
Received: April 21, 2021
© 2021 The American Congress of Rehabilitation Medicine. Published by Elsevier Inc. All rights reserved.