Barton et al's
1article studies cardiovascular risk in a cohort of individuals with a spinal cord injury. As the authors noted, the Framingham Risk Score (FRS) was derived to identify risk factors for cardiovascular disease. It is important to note, however, that the outcome measure for this risk score is defined as a “composite of coronary heart disease (coronary death, myocardial infarction, coronary insufficiency, and angina), cerebrovascular events (including ischemic stroke, hemorrhagic stroke, and transient ischemic attack), peripheral artery disease (intermittent claudication), and heart failure.”
- Barton TJ
- Low DA
- Bakker EA
- et al.
Traditional cardiovascular risk factors strongly underestimate the 5-year occurrence of cardiovascular morbidity and mortality in spinal cord injured individuals.
Arch Phys Med Rehabil. 2021; 102: 27-34
2(p744) This composite outcome does not include pulmonary embolism, chronic venous insufficiency, deep venous thrombosis, atrial fibrillation/flutter, aortic aneurysms, valve diseases, or dissection, as was used in Barton et al's study. These other outcomes, which are not meant to be predicted by the FRS, encompassed 22 of the 39 outcomes that were reported. Additionally, there were 7 deaths in this study from “other cardiovascular death” and it is unclear whether the etiology of these would fall with the composite outcome for the FRS. There were also 2 instances of peripheral vascular disease, an entity that includes, but is not specific to, peripheral artery disease, so it is unclear whether these outcomes fall within the FRS composite outcome.
- D'Agostino Sr, RB
- Vasan RS
- Pencina MJ
- et al.
General cardiovascular risk profile for use in primary care: the Framingham Heart Study.
Circulation. 2008; 117: 743-753
To read this article in full you will need to make a payment
Purchase one-time access:Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
One-time access price info
- For academic or personal research use, select 'Academic and Personal'
- For corporate R&D use, select 'Corporate R&D Professionals'
Subscribe:Subscribe to Archives of Physical Medicine and Rehabilitation
Already a print subscriber? Claim online access
Already an online subscriber? Sign in
Register: Create an account
Institutional Access: Sign in to ScienceDirect
- Traditional cardiovascular risk factors strongly underestimate the 5-year occurrence of cardiovascular morbidity and mortality in spinal cord injured individuals.Arch Phys Med Rehabil. 2021; 102: 27-34
- General cardiovascular risk profile for use in primary care: the Framingham Heart Study.Circulation. 2008; 117: 743-753
Published online: July 17, 2021
Accepted: April 5, 2021
Received: April 3, 2021
© 2021 The American Congress of Rehabilitation Medicine. Published by Elsevier Inc. All rights reserved.