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REVIEW ARTICLE| Volume 102, ISSUE 11, P2231-2238, November 2021

Is There an Association Between Ulnar Nerve Hypermobility and Neuropathy at the Elbow?

Published:March 11, 2021DOI:https://doi.org/10.1016/j.apmr.2021.02.021

      Abstract

      Objective

      To systematically review the association between ulnar nerve hypermobility (UNH) at the elbow and ulnar neuropathy (UNE).

      Data Sources

      Cumulative Index to Nursing and Allied Health, MEDLINE, and Embase databases were searched for English language studies published up to July 4, 2020.

      Study Selection

      We included case-control, cohort, and randomized controlled studies that established the presence or absence of UNH and UNE. Twenty out of 654 studies identified met the inclusion criteria.

      Data Extraction

      Two reviewers independently extracted data for analysis. Risk of bias and applicability were assessed with the QUADAS-2 tool.

      Data Synthesis

      We compared rates of UNH between patients diagnosed with and without UNE and found no significant difference. The meta-analysis pooled rate of UNH was 0.37 (95% confidence interval, 0.20-0.57) for those without UNE and 0.33 (95% confidence interval, 0.23-0.45) for those with UNE.

      Conclusions

      The clinical finding of UNH is unhelpful when assessing for UNE, as the presence of UNH does not make the diagnosis of UNE more likely.

      Keywords

      List of abbreviations:

      CI (confidence interval), CSA (cross-sectional area), UND (ulnar nerve dislocation), UNE (ulnar neuropathy at the elbow), UNH (ulnar nerve hypermobility), UNS (ulnar nerve subluxation)
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