Advertisement
Original research| Volume 102, ISSUE 8, P1514-1523, August 2021

Determinants of Discharge Disposition From Acute Care for Survivors of Hypoxic-Ischemic Brain Injury: Results From a Large Population-Based Cohort Data Set

  • Binu Jacob
    Correspondence
    Corresponding author Binu Jacob, MSc, PhD, University Health Network, Toronto, Ontario, Canada.
    Affiliations
    KITE-Toronto Rehabilitation Institute, University Health Network, Toronto, Ontario Canada

    Toronto General Hospital, University Health Network, Toronto, Ontario Canada
    Search for articles by this author
  • Vincy Chan
    Affiliations
    KITE-Toronto Rehabilitation Institute, University Health Network, Toronto, Ontario Canada

    Rehabilitation Sciences Institute, University of Toronto, Toronto, Ontario Canada
    Search for articles by this author
  • David Stock
    Affiliations
    KITE-Toronto Rehabilitation Institute, University Health Network, Toronto, Ontario Canada

    Clinical Health and Epidemiology, Dalhousie University, Halifax, Nova Scotia, Canada
    Search for articles by this author
  • Angela Colantonio
    Affiliations
    KITE-Toronto Rehabilitation Institute, University Health Network, Toronto, Ontario Canada

    Rehabilitation Sciences Institute, University of Toronto, Toronto, Ontario Canada

    Department of Occupational Science & Occupational Therapy, University of Toronto, Toronto, Ontario, Canada

    Institute for Clinical Evaluative Sciences, Toronto, Ontario Canada
    Search for articles by this author
  • Nora Cullen
    Affiliations
    KITE-Toronto Rehabilitation Institute, University Health Network, Toronto, Ontario Canada

    Rehabilitation Sciences Institute, University of Toronto, Toronto, Ontario Canada

    McMaster University, Hamilton Health Science Centre, and St Joseph’s Healthcare, Hamilton, Ontario, Canada
    Search for articles by this author
Published:February 17, 2021DOI:https://doi.org/10.1016/j.apmr.2021.01.083

      Abstract

      Objective

      To identify determinants of discharge disposition from acute care among survivors of hypoxic-ischemic brain injury (HIBI), stratified by sex.

      Design

      Population-based retrospective cohort study using provincial data in Ontario, Canada. The determinants were grouped into predisposing, need, and enabling factors using the Anderson Behavioral Model.

      Setting

      Acute care.

      Participants

      Survivors of HIBI aged ≥20 years at the time of hospitalization and discharged alive from acute care between April 1, 2002, and March 31, 2017. There were 7492 patients with HIBI, of whom 28% (N=2077) survived their acute care episode.

      Interventions

      Not applicable.

      Main Outcome Measures

      Discharge disposition from acute care, categorized as complex continuing care (CCC), long-term care (LTC), inpatient rehabilitation (IR), home with support, home without support, and transferred to another acute care.

      Results

      The discharge dispositions for the 2077 survivors were IR 23.4% (n=487), CCC 19.5% (n=404), LTC 6.2% (n=128), home without support 31.2% (n=647), home with support 15.1% (n=314), and other 4.6%. Multinomial multivariable logistic regression analysis using home without support as the reference category revealed that female patients were significantly more likely than male patients to be discharged to LTC/CCC. Those who were older, were frail, and had longer stay in acute care or special care unit (SCU) were more likely to be discharged to LTC/CCC. The only significant determinant for IR was longer stay in acute care. Survivors with cardiac-related injury were less likely to be discharged to LTC/CCC. Income was a significant factor for male patients but not for female patients in the sex-stratified analysis. The following variables were investigated but were not significant determinants in this study: need factors (comorbidity score, prior psychiatric disorders, health care utilization) and enabling factors (income quintile, rural area of residence).

      Conclusions

      Predisposing (age, sex) and need factors (frailty, acute care days, SCU days, type of injury) were significant determinants of discharge disposition from acute care after HIBI. In spite of a system with universal coverage, sex differences were found, with more female patients being discharged to CCC/LTC rather than IR, controlling for age and other confounders. These findings should be considered in appropriate discharge planning from acute care for survivors of HIBI.

      Keywords

      List of abbreviations:

      ABI (acquired brain injury), ACG (Adjusted Clinical Group), ADG (Aggregated Diagnosis Group), ALC (alternate level of care), aOR (adjusted odds ratio), CCC (complex continuing care), CI (confidence interval), DAD (Discharge Abstract Database), HIBI (hypoxic-ischemic brain injury), IR (inpatient rehabilitation), LOS (length of stay), LTC (long-term care), OR (odds ratio), SCU (special care unit), TBI (traumatic brain injury)
      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'

      Subscribe:

      Subscribe to Archives of Physical Medicine and Rehabilitation
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect

      References

        • Jette D.U.
        • Grover L.
        • Keck C.P.
        A qualitative study of clinical decision making in recommending discharge placement from the acute care setting.
        Phys Ther. 2003; 83: 224-236
        • Zarshenas S.
        • Colantonio A.
        • Alavinia S.M.
        • Jaglal S.
        • Tam L.
        • Cullen N.
        Predictors of discharge destination from acute care in patients with traumatic brain injury: a systematic review.
        J Head Trauma Rehabil. 2019; 34: 52-64
        • Cuthbert J.P.
        • Corrigan J.D.
        • Harrison-Felix C.
        • et al.
        Factors that predict acute hospitalization discharge disposition for adults with moderate to severe traumatic brain injury.
        Arch Phys Med Rehabil. 2011; 92: 721-730
      1. Rehabilitation, complex and long-term care. Charting a course for the health system and nursing in Ontario.
        (Available at:)
        • Ontario Ministry of Health and Long-Term Care
        Hospital chronic care co-payment: questions and answers.
        (Available at:)
      2. Ontario Ministry of Health and Long-Term Care. Home, community and residential care services.
        (Available at:)
        • Cullen N.K.
        • Weisz K.
        Cognitive correlates with functional outcomes after anoxic brain injury: a case-controlled comparison with traumatic brain injury.
        Brain Inj. 2011; 25: 35-43
        • Cullen N.K.
        • Crescini C.
        • Bayley M.T.
        Rehabilitation outcomes after anoxic brain injury: a case-controlled comparison with traumatic brain injury.
        PM R. 2009; 1: 1069-1076
        • Cullen N.
        • Chundamala J.
        • Bayley M.
        • Jutai J.
        • Erabi G.
        The efficacy of acquired brain injury rehabilitation.
        Brain Inj. 2007; 21: 113-132
        • Stock D.
        • Jacob B.
        • Chan V.
        • Colantonio A.
        • Cullen N.
        Change in function over inpatient rehabilitation after hypoxic ischemic brain injury: a population-wide cohort study.
        Arch Phys Med Rehabil. 2019; 100: 1640-1647
        • Stock D.
        • Cowie C.
        • Chan V.
        • et al.
        Determinants of alternate-level-of-care delayed discharge among acute care survivors of hypoxic-ischemic brain injury: a population-based cohort study.
        CMAJ Open. 2016; 4: E689-E697
        • Jacob B.
        • Stock D.
        • Chan V.
        • Colantonio A.
        • Cullen N.
        Predictors of in-hospital mortality following hypoxic-ischemic brain injury: a population-based study.
        Brain Inj. 2020; 34: 178-186
        • Chen A.Y.
        • Zagorski B.
        • Parsons D.
        • Vander Laan R.
        • Chan V.
        • Colantonio A.
        Factors associated with discharge destination from acute care after acquired brain injury in Ontario, Canada.
        BMC Neurol. 2012; 12: 16
        • Janus T.J.
        • Smith H.L.
        • Chigazola A.
        • Wortman M.R.
        • Sidwell R.A.
        • Piper J.G.
        Hospital discharge destinations for Hispanic and non-Hispanic White patients treated for traumatic brain injury.
        J Trauma Nurs. 2013; 20 ([quiz 8-9]): 102-107
        • Harbinson M.
        • Zarshenas S.
        • Cullen N.K.
        Long-term functional and psychosocial outcomes after hypoxic-ischemic brain injury: a case-controlled comparison to traumatic brain injury.
        PM R. 2017; 9: 1200-1207
        • Cullen N.K.
        • Park Y.G.
        • Bayley M.T.
        Functional recovery following traumatic vs non-traumatic brain injury: a case-controlled study.
        Brain Inj. 2008; 22: 1013-1020
        • Wilson B.A.
        Cognitive functioning of adult survivors of cerebral hypoxia.
        Brain Inj. 1996; 10: 863-874
        • Chan V.
        • Stock D.
        • Jacob B.
        • Cullen N.
        • Colantonio A.
        Readmission following hypoxic ischemic brain injury: a population-based cohort study.
        CMAJ Open. 2018; 6: E568-E574
        • Phillips S.P.
        Defining and measuring gender: a social determinant of health whose time has come.
        Int J Equity Health. 2005; 4: 11
        • Stock D.
        • Cowie C.
        • Chan V.
        • Cullen N.
        • Colantonio A.
        Determinants of admission to inpatient rehabilitation among acute care survivors of hypoxic-ischemic brain injury: a prospective population-wide cohort study.
        Arch Phys Med Rehabil. 2016; 97: 885-891
      3. Canadian Institute for Health Information. Acute and ambulatory care data content standard. Available at: https://secure.cihi.ca/free_products/acute-ambulatory-care-data-content-standard-june-2017-en.pdf. Accessed March 11, 2021.

        • Juurlink D.
        • Preyra C.
        • Croxford R.
        • et al.
        Canadian Institute for Health Information Discharge Abstract Database: a validaiton study.
        Institute for Health Evalautive Sciences, Toronto, 2006
        • Ramdass S.K.
        • Brennan M.J.
        • Starr R.
        • et al.
        The association of frailty with discharge disposition for hospitalized community dwelling elderly patients.
        J Hosp Med. 2018; 13: 182-184
        • Hirshfield S.
        • Downing Jr., M.J.
        • Horvath K.J.
        • Swartz J.A.
        • Chiasson M.A.
        Adapting Andersen's Behavioral Model of Health Service Use to examine risk factors for hypertension among U.S. MSM.
        Am J Mens Health. 2018; 12: 788-797
        • Babitsch B.
        • Gohl D.
        • von Lengerke T.
        Re-revisiting Andersen's Behavioral Model of Health Services Use: a systematic review of studies from 1998-2011.
        Psychosoc Med. 2012; 9: Doc11
        • Andersen R.
        • Newman J.F.
        Societal and individual determinants of medical care utilization in the United States.
        Milbank Mem Fund Q Health Soc. 1973; 51: 95-124
        • Austin P.C.
        • van Walraven C.
        • Wodchis W.P.
        • Newman A.
        • Anderson G.M.
        Using the Johns Hopkins Aggregated Diagnosis Groups (ADGs) to predict mortality in a general adult population cohort in Ontario, Canada.
        Med Care. 2011; 49: 932-939
      4. The John Hopkins Adjusted Clinical Groups technical reference guide, version 10. John Hopkins University, Baltimore2009
        • Xue Q.L.
        The frailty syndrome: definition and natural history.
        Clin Geriatr Med. 2011; 27: 1-15
        • McIsaac D.I.
        • Bryson G.L.
        • van Walraven C.
        Association of frailty and 1-year postoperative mortality following major elective noncardiac surgery: a population-based cohort study.
        JAMA Surg. 2016; 151: 538-545
      5. Statistics C. 2018 Statistics Canada – Canadian Housing Statistics Program 46-10-0050-01: Total family income and owner characteristics at the residential property level by income quintiles. V1 ed.: Scholars Portal Dataverse; 2020.

        • Statistics Canada
        Census dictionary.
        Statistics Canada, Ottawa, ON2016
        • Rittenberger J.C.
        • Raina K.
        • Holm M.B.
        • Kim Y.J.
        • Callaway C.W.
        Association between Cerebral Performance Category, Modified Rankin Scale, and discharge disposition after cardiac arrest.
        Resuscitation. 2011; 82: 1036-1040
        • Holroyd-Leduc J.M.
        • Kapral M.K.
        • Austin P.C.
        • Tu J.V.
        Sex differences and similarities in the management and outcome of stroke patients.
        Stroke. 2000; 31: 1833-1837
        • Brown S.B.
        • Colantonio A.
        • Kim H.
        Gender differences in discharge destination among older adults following traumatic brain injury.
        Health Care Women Int. 2012; 33: 896-904
        • Amador L.F.
        • Reyes-Ortiz C.A.
        • Reed D.
        • Lehman C.
        Discharge destination from an acute care for the elderly (ACE) unit.
        Clin Interv Aging. 2007; 2: 395-399
        • Wagner A.K.
        • Hammond F.M.
        • Grigsby J.H.
        • Norton H.J.
        The value of trauma scores: predicting discharge after traumatic brain injury.
        Am J Phys Med Rehabil. 2000; 79: 235-242
        • Van Baalen B.
        • Odding E.
        • Stam H.J.
        Cognitive status at discharge from the hospital determines discharge destination in traumatic brain injury patients.
        Brain Inj. 2008; 22: 25-32
        • Chen A.
        • Bushmeneva K.
        • Zagorski B.
        • Colantonio A.
        • Parsons D.
        • Wodchis W.P.
        Direct cost associated with acquired brain injury in Ontario.
        BMC Neurol. 2012; 12: 76
        • Allen L.A.
        • Hernandez A.F.
        • Peterson E.D.
        • et al.
        Discharge to a skilled nursing facility and subsequent clinical outcomes among older patients hospitalized for heart failure.
        Circ Heart Fail. 2011; 4: 293-300
        • Chan L.
        • Doctor J.
        • Temkin N.
        • et al.
        Discharge disposition from acute care after traumatic brain injury: the effect of insurance type.
        Arch Phys Med Rehabil. 2001; 82: 1151-1154
        • Kim H.
        • Colantonio A.
        • Deber R.
        • Vernich L.
        Discharge destination from acute care after traumatic brain injury.
        Can J Neurol Sci. 2006; 33: 48-52
        • Chang P.F.
        • Ostir G.V.
        • Kuo Y.F.
        • Granger C.V.
        • Ottenbacher K.J.
        Ethnic differences in discharge destination among older patients with traumatic brain injury.
        Arch Phys Med Rehabil. 2008; 89: 231-236
        • Huber D.L.
        • McClelland E.
        Patient preferences and discharge planning transitions.
        J Prof Nurs. 2003; 19: 204-210
        • Kramer A.M.
        • Steiner J.F.
        • Schlenker R.E.
        • et al.
        Outcomes and costs after hip fracture and stroke. A comparison of rehabilitation settings.
        JAMA. 1997; 277: 396-404