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Original research| Volume 102, ISSUE 4, P664-674, April 2021

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Core Domains for Research on Hospital Inactivity in Acutely Ill Older Adults: A Delphi Consensus Study

Published:November 27, 2020DOI:https://doi.org/10.1016/j.apmr.2020.10.136

      HIGHLIGHTS

      • This research determined core domains (important types of outcomes).
      • Findings are for studies of physical activity in hospitalized older adults.
      • Findings may also improve outcome reporting in studies of sedentary behavior.
      • Use of a consensus approach with researchers, clinicians, policymakers, and patients.
      • Core domains provide the starting point for developing a core outcome set.

      Abstract

      Objective

      To identify core domains for research studies of physical activity and sedentary behavior during hospitalization for older adults with an acute medical illness.

      Design

      A 4-Round Delphi consensus process. Round 1 invited responses to open-ended questions to generate items for the core domains research. In rounds 2-4, participants were invited to use a Likert scale (1-9) to rate the importance of each core domain for research studies of physical activity and/or sedentary behavior in hospitalized older adults with an acute medical illness.

      Setting

      Online surveys.

      Participants

      A total of 49 participants were invited to each round (international researchers, clinicians, policy makers and patients). Response rates across rounds 1-4 were 94%, 88%, 83% and 81%, respectively.

      Interventions

      None.

      Main Outcome Measures

      Consensus was defined a priori as ≥70% of respondents rating an item as “critical” (score≥7) and ≤15% of respondents rating an item as “not important” (score≤3).

      Results

      In round 2, a total of 9 of 25 core domains reached consensus agreement (physical functioning, general, role functioning, emotional functioning, global quality of life, hospital, psychiatric, cognitive functioning, carer burden). In round 3, an additional 8 reached consensus (adverse events, perceived health status, musculoskeletal, social functioning, vascular, cardiac, mortality, economic). Round 4 participants provided further review and a final rating of all 17 core domains that met consensus in previous rounds. Four core domains were rated as “critically important” to evaluate: physical functioning, social functioning, emotional functioning, and hospital outcomes.

      Conclusions

      This preliminary work provides international and expert consensus-based core domains for development toward a core-outcome set for research, with the ultimate goal of fostering consistency in outcomes and reporting to accelerate research on effective strategies to address physical activity and/or sedentary behavior in older adults while hospitalized.

      Keywords

      List of abbreviations:

      COMET (Core Outcome Measures in Effectiveness Trials), COS (core outcome set)
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