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Original research| Volume 101, ISSUE 9, P1563-1569, September 2020

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Estimation of Physical Activity Intensity in Spinal Cord Injury Using a Wrist-Worn ActiGraph Monitor

  • Akhila Veerubhotla
    Affiliations
    Department of Rehabilitation Sciences and Technology, School of Health and Rehabilitation Sciences, University of Pittsburgh, Pittsburgh, PA

    Human Engineering Research Laboratories, Department of Veteran Affairs Pittsburgh Healthcare System, Pittsburgh, PA
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  • EunKyoung Hong
    Affiliations
    Spinal Cord Damage Research Center, James J Peters VA Medical Center, Bronx, NY

    Department of Rehabilitation and Human Performance, Icahn School of Medicine at Mount Sinai, New York, NY
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  • Steven Knezevic
    Affiliations
    VA Rehabilitation Research & Development Service, National Center of Excellence for the Medical Consequences of Spinal Cord Injury, James J. Peters VA Medical Center, Bronx, NY
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  • Ann Spungen
    Affiliations
    Spinal Cord Damage Research Center, James J Peters VA Medical Center, Bronx, NY

    VA Rehabilitation Research & Development Service, National Center of Excellence for the Medical Consequences of Spinal Cord Injury, James J. Peters VA Medical Center, Bronx, NY
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  • Dan Ding
    Correspondence
    Corresponding author Dan Ding, PhD, Human Engineering Research Laboratories, Department of Veteran Affairs Pittsburgh Healthcare System, 6425 Penn Avenue, Suite 400, Pittsburgh, PA 15206.
    Affiliations
    Department of Rehabilitation Sciences and Technology, School of Health and Rehabilitation Sciences, University of Pittsburgh, Pittsburgh, PA

    Human Engineering Research Laboratories, Department of Veteran Affairs Pittsburgh Healthcare System, Pittsburgh, PA
    Search for articles by this author

      Abstract

      Objectives

      To derive accelerometer count thresholds for classifying time spent in sedentary, light intensity, and moderate-to-vigorous physical activity (MVPA) in manual wheelchair users (MWUs) with spinal cord injury (SCI).

      Design

      Participants completed 18 activities of daily living and exercises for 10 minutes each with a 3-minute break between activities while wearing a COSMED K4b2 portable metabolic cart and an ActiGraph activity monitor on the dominant wrist. A linear regression was computed between the wrist acceleration vector magnitude and SCI metabolic equivalent of task (MET) for 80% of the participants to obtain thresholds for classifying different activity intensities, and the obtained thresholds were tested for accuracy on the remaining 20% of participants. This cross-validation process was iterated for 1000 times to evaluate the stability of the thresholds on data corresponding to different proportions of sedentary, light intensity, and MVPA. MET values of 1.5 or lower were classified as sedentary behavior, MET values between 1.5 and 3 were classified as light intensity, and MET values of 3 or higher were classified as MVPA. The final thresholds were then validated on an out-of-sample independent dataset.

      Participants

      MWUs (N=17) with SCI in the out-of-sample validation data set.

      Interventions

      Not applicable.

      Setting

      Research lab, community

      Main Outcome Measures

      Accelerometer thresholds to classify sedentary, light intensity, and MVPA were obtained and their accuracy tested using cross-validation and an out-of-sample dataset.

      Results

      The threshold between sedentary and light intensity was 2057 counts-per-minute, and the threshold between light intensity and MVPA was 11,551 counts per minute. Based on the out-of-sample validation, the obtained thresholds had an overall accuracy of 85.6%, with a sensitivity and specificity of 95.3% and 97.4% for sedentary behavior, 87.8% and 84.5% for light intensity, 68.5% and 96.3% for MVPA, respectively.

      Conclusion

      Accelerometer-based thresholds can be used to accurately identify sedentary behavior. However, thresholds may not provide accurate estimations of MVPA throughout the day when participants engage in more resistance-based activities.

      Keywords

      List of abbreviations:

      ADL (activities of daily living), CI (confidence interval), CPM (counts per minute), HERL (Human Engineering Research Lab), ICC (intraclass correlation coefficient), LOA (limits of agreement), MCCV (Monte Carlo cross-validation), MET (metabolic equivalent of task), MVPA (moderate-to-vigorous physical activity), MWU (manual wheelchair user), PA (physical activity), ROC-AUC (area under the receiver operating characteristic curve), SCI (spinal cord injury), VM (vector magnitude), V̇o2 (oxygen consumption per unit time)
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