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Original research| Volume 101, ISSUE 10, P1711-1719, October 2020

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Factors Associated With Health-Related Quality of Life in People Living With Partial Foot or Transtibial Amputation

      Abstract

      Objectives

      To determine which demographic, amputation, and health-related factors were associated with health-related quality of life (HR-QoL) in people living with partial foot amputation (PFA) or transtibial amputation (TTA).

      Design

      Cross-sectional survey.

      Setting

      Community.

      Participants

      Adults (N=123) with unilateral PFA (n=42) or TTA (n=81).

      Intervention

      Not applicable.

      Main Outcome Measure

      Medical Outcome Short Form (SF-36) version 2.

      Results

      Variation in the SF-36 Physical or Mental Component Summary scores were associated with complex interactions between factors, including: time since amputation, fatigue, anxiety, depression, pain interference, and physical function. Level of amputation (ie, PFA or TTA) did not explain a significant part of the variation in either the SF-36 Physical or Mental Component Summary scores.

      Conclusions

      Given the complex interactions between factors associated with the physical and mental health components of HR-QoL, there are opportunities to consider the long-term holistic care required by people living in the community with PFA or TTA.

      Keywords

      List of abbreviations:

      GLM (generalized linear model), HR-QoL (health-related quality of life), ISO (International Standards Organization), IV (independent variable), MCS (mental component summary), PCS (physical component summary), PFA (partial foot amputation), PROMIS-29v2 (Patient-Reported Outcomes Measures Information System version 2), SF-36v2 (Medical Outcome Short Form 36 version 2), TTA (transtibial amputation)
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