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Response to Letter Regarding “A Randomized Controlled Trial on the Effects of Low-Dose Extracorporeal Shockwave Therapy in Patients With Knee Osteoarthritis”

      We would like to express our appreciation to the authors of the letter to the editor for their interest in our recent article.
      • Zhong Z.
      • Liu B.
      • Liu G.
      • Chen J.
      • Li Y.
      • Chen J.
      • et al.
      A randomized controlled trial on the effects of low-dose extracorporeal shockwave therapy in patients with knee osteoarthritis.
      They argued that the control group in our study should be considered a very low dose extracorporeal shockwave therapy (ESWT) group rather than a placebo. We see their comments as an opportunity to provide more insight into designing a placebo in the ESWT study. The following is our explanation of the control group as a placebo group in our trial.
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      References

        • Zhong Z.
        • Liu B.
        • Liu G.
        • Chen J.
        • Li Y.
        • Chen J.
        • et al.
        A randomized controlled trial on the effects of low-dose extracorporeal shockwave therapy in patients with knee osteoarthritis.
        Arch Phys Med Rehabil. 2019; 100: 1695-1702
        • Rompe J.D.
        • Decking J.
        • Schoellner C.
        • Theis C.
        Repetitive low-energy shock wave treatment for chronic lateral epicondylitis in tennis players.
        Am J Sports Med. 2004; 32: 734-743
        • Gerdesmeyer L.
        • Wagenpfeil S.
        • Haake M.
        • Maier M.
        • Loew M.
        • Wortler K.
        • et al.
        Extracorporeal shock wave therapy for the treatment of chronic calcifying tendonitis of the rotator cuff: a randomized controlled trial.
        JAMA. 2003; 290: 2573-2580
        • Buchbinder R.
        • Ptasznik R.
        • Gordon J.
        • Buchanan J.
        • Prabaharan V.
        • Forbes A.
        Ultrasound-guided extracorporeal shock wave therapy for plantar fasciitis: a randomized controlled trial.
        JAMA. 2002; 288: 1364-1372
        • Yang T.H.
        • Huang Y.C.
        • Lau Y.C.
        • Wang L.Y.
        Efficacy of radial extracorporeal shock wave therapy on lateral epicondylosis, and changes in the common extensor tendon stiffness with pretherapy and posttherapy in real-time sonoelastography: a arandomized controlled study.
        Am J Phys Med Rehabil. 2017; 96: 93-100

      Linked Article

      • Extracorporeal Shockwave Therapy and Knee Osteoarthritis: Defining a Placebo Group
        Archives of Physical Medicine and RehabilitationVol. 101Issue 7
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          In the recently published study by Zhong et al, “A Randomized Controlled Trial on the Effects of Low-Dose Extracorporeal Shockwave Therapy in Patients With Knee Osteoarthritis,” the researchers studied low-dose extracorporeal shockwave therapy (ESWT) treatment in patients with knee osteoarthritis. They stated that ESWT was superior to placebo in both pain and functional improvement, as well as in terms of negative effects on the articular cartilage.
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