Highlights
- •Change in peak oxygen consumption per unit time (VO2peak) was highly variable following an 8-week aerobic cycling program.
- •Higher pedaling cadence during cycling was predictive of improvements in VO2peak.
- •Low baseline VO2peak was also predictive of improvements in VO2peak postexercise.
- •Aerobic intensity did not predict change in VO2peak in persons with chronic stroke.
Abstract
Objective
To determine demographic and physiological factors that predict improvement in aerobic
capacity among individuals with chronic stroke participating in cycling interventions.
Design
Secondary analysis of data from 2 randomized clinical trials.
Setting
Research laboratory.
Participants
Individuals with chronic stroke (N=44).
Interventions
Participants were randomized to one of the following interventions: forced aerobic
exercise and upper extremity repetitive task practice (FE+UERTP, n=16), voluntary
aerobic exercise and upper extremity repetitive task practice (VE+UERTP, n=15), or
a nonaerobic control group (control, n=13). All interventions were time-matched and
occurred 3 times per week for 8 weeks.
Main Outcome Measure
Aerobic capacity as measured by peak oxygen consumption per unit time (VO2peak) during maximal cardiopulmonary exercise stress testing.
Results
Significant improvements in VO2peak were observed from baseline to postintervention in the VE+UERTP group (P<.001). Considerable variability was observed among participants relating to postintervention
change in VO2peak. Among aerobic exercise participants, a multivariate regression analysis revealed
that cycling cadence, baseline VO2peak, and group allocation were significant predictors of change in VO2peak.
Conclusions
High exercise rate (cycling cadence) appears to be an important variable in improving
aerobic capacity and should be considered when prescribing aerobic exercise for individuals
with chronic stroke. Those with low VO2peak at baseline may benefit the most from aerobic interventions as it relates to cardiorespiratory
fitness. Further investigation is warranted to understand the precise role of other
exercise and demographic variables in the prescription of aerobic exercise for this
population and their effects on secondary stroke prevention and mortality.
Keywords
List of abbreviations:
CPX (cardiopulmonary exercise), FE (forced aerobic exercise), FE+UERTP (forced aerobic exercise and upper extremity repetitive task practice), VE+UERTP (voluntary aerobic exercise and upper extremity repetitive task practice), VE (voluntary aerobic exercise), VO2peak (peak oxygen consumption per unit time)To read this article in full you will need to make a payment
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Article info
Publication history
Published online: November 25, 2019
Footnotes
Clinical Trial Registration Nos.: NCT02076776 and NCT02494518.
Supported by the National Institute of Neurological Disorders and Stroke (grant no. R03HD073566) and the American Heart Association (grant no. 15MCPRP25700312). The funders had no role in data collection and analysis or preparation of the manuscript.
Disclosures: Jay L. Alberts has authored intellectual property protecting the algorithm associated with the forced exercise bicycle. The other authors have nothing to disclose.
Identification
Copyright
© 2019 by the American Congress of Rehabilitation Medicine
