Abstract
Objective
This study aimed to quantitatively investigate the existence of differences in spatiotemporal
and kinematic parameters of gait in men and women with Parkinson disease (PD) using
computerized 3-dimensional gait analysis.
Design
Retrospective cohort study.
Setting
Laboratory of Biomechanics.
Participants
Individuals with PD (N=35; 17 female, 18 male) of mean age 70.7 years characterized
by mild disability (Hoehn and Yahr ≤2.5) who were tested in On medication state approximately
60 to 90 minutes after intake of the usual morning Levodopa dose.
Intervention
Not applicable.
Main Outcome Measures
Spatiotemporal parameters of gait (speed, stride length, cadence, step width, duration
of stance, swing, double support phases) and kinematics of hip, knee, and ankle joints
in the sagittal plane.
Results
Men and women exhibit similar spatiotemporal parameters, except for step width (wider
in men). In contrast, relevant differences were found in terms of ankle kinematics.
In particular, women presented increased ankle dorsiflexion through all the stance
phase and mid to late swing phase, and reduced plantarflexion at the stance-swing
phase transition.
Conclusions
Gait patterns of men and women with PD with mild disability are similar in terms of
spatiotemporal parameters but characterized by marked differences regarding the ankle
kinematics on the sagittal plane. The findings of the present study support the concept
that investigations seeking to clarify the complex pathophysiology of PD-related gait
disturbances should consider the role played by an individual's sex, thereby achieving
more effective designing of physical and rehabilitative treatments.
Keywords
List of abbreviations:
ANOVA (analysis of variance), MANOVA (multivariate analysis of variance), PD (Parkinson disease), ROM (range of motion)To read this article in full you will need to make a payment
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References
- The biomechanics and motor control of gait in Parkinson disease.Clin Biomech (Bristol, Avon). 2001; 16: 459-470
- Walking stability using harmonic ratios in Parkinson's disease.Mov Disord. 2009; 24: 261-267
- Gait dynamics in Parkinson's disease: common and distinct behavior among stride length, gait variability, and fractal-like scaling.Chaos. 2009; 19026113
- Determinants of disability and quality of life in mild to moderate Parkinson disease.Neurology. 2008; 70: 2241-2247
- Gait disorders in Parkinson’s disease: assessment and management.Int J Geront. 2013; 7: 189-193
- Quantitative gait analysis in Parkinson's disease: comparison with a healthy control group.Arch Phys Med Rehabil. 2005; 86: 1007-1013
- Gait analysis comparing Parkinson's disease with healthy elderly subjects.Arq Neuropsiquiatr. 2010; 68: 81-86
Corona F, Pau M, Guicciardi M, Murgia M, Pili R, Casula C. Quantitative assessment of gait in elderly people affected by Parkinson’s disease. Paper presented at: IEEE International Symposium on Medical Measurements and Applications (MeMeA). May 15-18, 2016; Benevento, Italy.
- Gait analysis and clinical correlations in early Parkinson's disease.Funct Neurol. 2017; 32: 28-34
- Leg muscle activation during gait in Parkinson's disease: adaptation and interlimb coordination.Electroencephalogr Clin Neurophysiol. 1995; 97: 408-415
- Electromyographical gait characteristics in Parkinson's disease: effects of combined physical therapy and rhythmic auditory stimulation.Front Neurol. 2018; 9: 211
- Gender differences in Parkinson's disease: a clinical perspective.Acta Neurol Scand. 2017; 136: 570-584
- The relevance of gender in Parkinson's disease: a review.J Neurol. 2017; 264: 1583-1607
- Do men and women walk differently? A review and meta-analysis of sex difference in non-pathological gait kinematics. Air Force Research Laboratory Interim Report AFRL-RH-WP-TR-2014-0016.(Available at:)http://www.dtic.mil/dtic/tr/fulltext/u2/a597428.pdfDate accessed: January 21, 2019
- Do gait patterns differ in men and women with multiple sclerosis?.Mult Scler Relat Disord. 2017; 18: 202-208
- Gender differences in gait kinematics for patients with knee osteoarthritis.BMC Musculoskelet Disord. 2016; 17: 157
- Gait abnormalities before and after total hip arthroplasty differ in men and women.J Biomech. 2016; 49: 3582-3586
- Sex differences in gait after total knee arthroplasty.J Arthroplasty. 2018; 33: 897-902
- Men and women with Down syndrome exhibit different kinematic (but not spatio-temporal) gait patterns.J Intellect Disabil Res. 2019; 63: 64-71
- The relevance of the Lewy body to the pathogenesis of idiopathic Parkinson’s disease.J Neurol Neurosurg Psychiatry. 1988; 51: 745-752
- Effects of physical rehabilitation integrated with rhythmic auditory stimulation on spatio-temporal and kinematic parameters of gait in Parkinson's disease.Front Neurol. 2016; 7: 126
- The use of footstep sounds as rhythmic auditory stimulation for gait rehabilitation in Parkinson's disease: a randomized controlled trial.Front Neurol. 2018; 24: 348
- Association between objectively measured physical activity and gait patterns in people with Parkinson's disease: results from a 3-month monitoring.Parkinsons Dis. 2018; 2018: 7806574
- The kinematics and energy variations of swing-through crutch gait.J Biomech. 1979; 12: 579-585
- Kinematics of walking frame ambulation.Clin Biomech (Bristol, Avon). 1993; 8: 31-36
- A gait analysis data collection and reduction technique.Hum Mov Sci. 1991; 10: 575-587
- Comprehensive non-dimensional normalization of gait data.Gait Posture. 2016; 44: 68-73
- Sex differences in whole body gait kinematics at preferred speeds.Gait Posture. 2015; 41: 540-545
- Two feet, or one person? Problems associated with statistical analysis of paired data in foot and ankle medicine.Foot. 2004; 14: 2-5
- Analysis of data collected from right and left limbs: accounting for dependence and improving statistical efficiency in musculoskeletal research.Gait Posture. 2018; 59: 182-187
- Ageing and gait variability--a population-based study of older people.Age Ageing. 2010; 39: 191-197
- Normative spatiotemporal gait parameters in older adults.Gait Posture. 2011; 34: 111-118
- Sex-specific differences in gait patterns of healthy older adults: results from the Baltimore Longitudinal Study of Aging.J Biomech. 2011; 44: 1974-1979
- Gender differences in balance performance at the time of retirement.Clin Biomech (Bristol, Avon). 2005; 20: 330-335
- Gender differences in platform measures of balance in rural community-dwelling elders.Arch Gerontol Geriatr. 2005; 41: 201-209
- Gender differences in three dimensional gait analysis data from 98 healthy Korean adults.Clin Biomech (Bristol, Avon). 2004; 19: 145-152
- Biomechanical analysis of hip and knee joints during gait in elderly subjects.Acta Ortop Bras. 2007; 15: 267-271
- Reduced hip extension in the elderly: dynamic or postural?.Arch Phys Med Rehabil. 2005; 86: 1851-1854
- Stride length regulation in Parkinson's disease: the use of extrinsic, visual cues.Brain. 2000; 123: 2077-2090
- Gender differences in joint biomechanics during walking: normative study in young adults.Am J Phys Med Rehabil. 1998; 77: 2-7
- Influence of contraction type, speed, and joint angle on ankle muscle weakness in Parkinson's disease: implications for rehabilitation.Arch Phys Med Rehabil. 2012; 93: 2352-2359
- Gender-related differences in physical performance among seniors.J Aging Phys Act. 2005; 13: 239-253
- Leg muscle strength is reduced in Parkinson's disease and relates to the ability to rise from a chair.Mov Disord. 2003; 18: 157-162
- Isokinetic muscle strength of knee extensors in individuals with Parkinson’s disease.Fisioter Mov. 2013; 26: 803-811
- Leg-extension strength and chair-rise performance in elderly women with Parkinson's disease.J Aging Phys Act. 2004; 12: 511-524
- The influence of age and gender on motor and non-motor features of early Parkinson's disease: initial findings from the Oxford Parkinson Disease Center (OPDC) discovery cohort.Parkinsonism Relat Disord. 2014; 20: 99-105
- Impaired leg extensor strength in individuals with Parkinson disease and relatedness to functional mobility.Parkinsonism Relat Disord. 2009; 15: 776-780
- Applications of gait analysis in pediatric orthopaedics.Curr Orthopaed Pract. 2016; 27: 455-464
Article info
Publication history
Published online: May 16, 2019
Footnotes
Supported by University of Cagliari and A.O. G. Brotzu General Hospital.
Disclosures: none.
Identification
Copyright
© 2019 by the American Congress of Rehabilitation Medicine
