Abstract
Objectives
Examine the amount and nature of research activity in head and neck cancer (HNC) rehabilitation;
highlight publication trends, including information about the authors, settings, and
study designs; and identify gaps in the existing literature.
Data Sources
Eligible studies were identified using PubMed, Embase, and CINAHL databases.
Study Selection
Inclusion criteria included human subjects, English language, publication between
1/1/1990 and 4/30/2017, HNC patients at any timepoint in disease, and evaluation of
rehabilitation outcomes as described by the International Classification of Functioning,
Disability and Health (ICF) framework. Exclusion criteria included intervention or
outcome not specific to rehabilitation or the HNC population, and protocols or abstracts
without corresponding full manuscripts.
Data Extraction
An established 6-step scoping review framework was utilized to develop the review
protocol. A 3-level review was then performed. Data on eligible studies were collected
using a Research Electronic Data Capture (REDCap) tool.
Data Synthesis
Among 2201 publications, 258 met inclusion criteria. Publication rate increased by
390% over the study timeframe. Most studies were observational (n=150). Few were interventional
(n=35). The most common interventions focused on chewing or swallowing (n=14), followed
by exercise (n=10). Most primary outcome measures fit the ICF definition of impairment;
fewer fit the definitions of activity limitation or participation restriction.
Conclusions
Although research volume in HNC rehabilitation is increasing, the literature is dominated
by small (≤100 patients), outpatient-based observational studies involving chewing
or swallowing-related impairments. More prospective studies in multidisciplinary domains
across the cancer care continuum are needed. There is particular need for interventional
studies and prospective observational studies. Future studies should evaluate clinically-relevant
activity limitations and participation restrictions. Rehabilitation professionals
have an important role in the design of future HNC rehabilitation research.
Keywords
List of abbreviations:
HNC (head and neck cancer), ICF (International Classification of Functioning, Disability and Health), QOL (quality of life), REDCap (Research Electronic Data Capture)To read this article in full you will need to make a payment
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Article info
Publication history
Published online: May 10, 2019
Footnotes
Current affiliation for Herbert, Swedish Medical Center, Seattle, WA; Barksdale, Mayo Clinic, Rochester, MN.
Supported by the National Center for Advancing Translational Sciences of the National Institutes of Health (award no. UL1 TR002319) for REDCap use through the Institute of Translational Health Sciences.
Disclosures: none.
Identification
Copyright
© 2019 by the American Congress of Rehabilitation Medicine
