Abstract
Objective
To describe a systematic review and meta-analysis to identify if intradialytic exercise
improves the removal of solutes and the hemodialysis adequacy.
Data Sources
A systematic review and meta-analysis of randomized controlled trials (RCTs) were
performed. The sources were MEDLINE (via PubMed), Web of Science, LILACS, and SciELO,
from inception until July 2018.
Study Selection
Clinical trials including patients on chronic hemodialysis submitted to the intervention
of aerobic intradialytic exercise.
Data Extraction
Evaluating as outcomes the removal of solutes (creatinine, phosphate, potassium) and/or
adequacy parameters (Kt/V-urea).
Data Synthesis
The systematic review included 23 studies (7 evaluating the effect of 1 exercise session
and 16 evaluating the effect of training, lasting from 6 to 25 weeks). Eleven RCT
were included in the meta-analyses. It was observed that the aerobic intradialytic
exercise increased the Kt/V-urea (0.15; 95% confidence interval [95% CI], 0.08-0.21)
and decreased creatinine (–1.82 mg/dL; 95% CI, –2.50 to –1.13), despite the high heterogeneity
of the analysis. No differences were found in phosphorus and potassium removal.
Conclusion
The aerobic intradialytic exercise may be suggested to improve the Kt/V-urea and the
creatinine removal during the dialysis.
Keywords
List of abbreviations:
95% CI (95% confidence interval), HD (hemodialysis), RCT (randomized controlled trial)To read this article in full you will need to make a payment
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Article info
Publication history
Published online: March 25, 2019
Footnotes
Clinical Trial Registration No.: CRD42018099016.
Disclosures: none.
Identification
Copyright
© 2019 by the American Congress of Rehabilitation Medicine
