Abstract
Objective
The aim of this project was to determine the effects of lower extremity aerobic exercise
coupled with upper extremity repetitive task practice (RTP) on health-related quality
of life (HRQOL) and depressive symptomology in individuals with chronic stroke.
Design
Secondary analysis of data from 2 randomized controlled trials.
Setting
Research laboratory.
Participants
Individuals (N=40) with chronic stroke.
Interventions
Participants received one of the following interventions: forced exercise+RTP (FE+RTP,
n=16), voluntary exercise+RTP (VE+RTP, n=16), or stroke education+RTP (EDU+RTP, n=8).
All groups completed 24 sessions, each session lasting 90 minutes.
Main Outcome Measures
The Center for Epidemiological Studies-Depression Scale (CES-D) and Stroke Impact
Scale (SIS) were used to assess depressive symptomology and HRQOL.
Results
There were no significant group-by-time interactions for any of the SIS domains or
composite scores. Examining the individual groups following the intervention, those
in the FE+RTP and VE+RTP groups demonstrated significant improvements in the following
SIS domains: strength, mobility, hand function, activities of daily living, and the
physical composite. In addition, the FE+RTP group demonstrated significant improvements
in memory, cognitive composite, and percent recovery from stroke. The HRQOL did not
change in the EDU+RTP group. Although CES-D scores improved predominantly for those
in the FE+RTP group, these improvements were not statistically significant. Overall,
results were maintained at the 4-week follow-up.
Conclusion
Aerobic exercise, regardless of mode, preceding motor task practice may improve HRQOL
in patients with stroke. The potential of aerobic exercise to improve cardiorespiratory
endurance, motor outcomes, and HRQOL poststroke justifies its use to augment traditional
task practice.
Keywords
List of abbreviations:
ADL (activity of daily living), CES-D (Center for Epidemiological Studies-Depression), EDU (education), EOT (end of treatment), FE (forced exercise), HRQOL (health-related quality of life), PSD (poststroke depression), RTP (repetitive task practice), SIS (Stroke Impact Scale), UE (upper extremity), VE (voluntary exercise)To read this article in full you will need to make a payment
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Article info
Publication history
Published online: December 10, 2018
Footnotes
Supported by the National Institute of Neurological Disorders and Stroke (grant no. R03HD073566) and the American Heart Association (grant no. 15MCPRP25700312). The funders had no role in data collection and analysis or preparation of the manuscript.
Disclosure: J.L.A. has authored intellectual property associated with the algorithm used in the control of the forced exercise bicycle. The other authors have nothing to disclose.
Clinical Trial Registration No.: NCT02076776; NCT02494518.
Identification
Copyright
© 2018 by the American Congress of Rehabilitation Medicine
