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Correction

        In the article by Chatelle et al, Detection and Interpretation of Impossible and Improbable Coma Recovery Scale-Revised Scores, published in Archives of Physical Medicine and Rehabilitation 2016;97:1295-300 (10.1016/j.apmr.2016.02.009), Appendix 1 reports subscore combinations that are “impossible” to obtain if CRS-R administration and guidelines are followed properly. However, the authors have determined that these subscore combinations do not violate CRS-R administration or scoring rules. Consequently, the authors have re-analyzed all subscale scores, including the nine subscore combinations previously listed as “impossible,” using the methods described in the article. Of the nine subscore combinations previously listed as being “impossible”, five subscore pairs are now classified as being improbable. Five subscore pairs previously classified as being improbable are now classified as being probable. In sum, of the 1190 independent CRS-R profiles analyzed, 10.4% (36/345) of subscore combinations were classified as improbable, versus 10.7% (36/336) reported in the original manuscript. Below is a corrected Appendix 1 with improbable CRS-R score combinations and updated supplementary tables (available online only at http://www.archives-pmr.org) with the frequency of occurrence of all 345 subscore combinations in association with the corresponding Mahalanobis distance and probability level.

        Appendix

        AppendixList of improbable CRS-R subscore combinations
        Improbable subscore combinations
        Subscore 1Subscore 2Possible contributing factors (when scoring errors are ruled out)
        No auditory response (A0)
        Non-observed subscore combinations.
        Object recognition (V5)
        Non-observed subscore combinations.
        None
        Auditory startle (A1)
        Non-observed subscore combinations.
        Object recognition (V5)
        Non-observed subscore combinations.
        No auditory response (A0)
        Non-observed subscore combinations.
        Functional communication (C2)
        Non-observed subscore combinations.
        Localization to sound (A2)
        Non-observed subscore combinations.
        Functional communication (C2)
        Non-observed subscore combinations.
        No auditory response (A0)
        Non-observed subscore combinations.
        Functional object use (M6)
        Non-observed subscore combinations.
        Aphasia; Central deafness
        No auditory response (A0)
        Non-observed subscore combinations.
        Attention (Ar3)
        Non-observed subscore combinations.
        Auditory startle (A1)
        Non-observed subscore combinations.
        Functional object use (M6)
        Non-observed subscore combinations.
        Consistent command following (A4)
        Non-observed subscore combinations.
        Visual startle (V1)
        Non-observed subscore combinations.
        3rd and 4th cranial nerve palsy; Ocular apraxia; Visual agnosia
        Consistent command following (A4)
        Non-observed subscore combinations.
        Abnormal posturing (M1)
        Non-observed subscore combinations.
        Severe spasticity
        Consistent command following (A4)
        Non-observed subscore combinations.
        Unarousable/No eye-opening (Ar0)
        Non-observed subscore combinations.
        Bilateral ptosis
        Awake with preserved vision but unable to open the eyelids.
        ; Facial oedema
        Awake with preserved vision but unable to open the eyelids.
        ; Eyelid apraxia
        Awake with preserved vision but unable to open the eyelids.
        Blink to threat (V1)
        Non-observed subscore combinations.
        Functional object use (M6)
        Non-observed subscore combinations.
        Bilateral optic nerve damage; Terson’s syndrome; Cortical blindness
        Visual fixation (V2)
        Non-observed subscore combinations.
        Unarousable (Ar0)
        Non-observed subscore combinations.
        Ptosis
        Awake with preserved vision but unable to open the eyelids.
        ; Eyelid apraxia
        Awake with preserved vision but unable to open the eyelids.
        Object localization (V4)
        Non-observed subscore combinations.
        Unarousable (Ar0)
        Non-observed subscore combinations.
        Object localization (V4)
        Non-observed subscore combinations.
        No motor response (M0)
        Non-observed subscore combinations.
        None
        Object recognition (V5)
        Non-observed subscore combinations.
        Abnormal posturing (M1)
        Non-observed subscore combinations.
        Severe spasticity
        Object recognition (V5)
        Non-observed subscore combinations.
        Unarousable (Ar0)
        Non-observed subscore combinations.
        Ptosis
        Awake with preserved vision but unable to open the eyelids.
        ; Eyelid apraxia
        Awake with preserved vision but unable to open the eyelids.
        Functional object use (M6)
        Non-observed subscore combinations.
        Unarousable (Ar0)
        Non-observed subscore combinations.
        Functional communication (C2)
        Non-observed subscore combinations.
        Unarousable (Ar0)
        Non-observed subscore combinations.
        Auditory startle (A1)
        P<.001.
        Functional communication (C2)
        P<.001.
        None
        Reproducible command following (A3)
        P<.001.
        Functional communication (C2)
        P<.001.
        N/A
        These combinations are clinically expected and likely to be improbable due to the population included in the sample (mainly VS/MCS patients).
        Consistent command following (A4)
        P<.001.
        No visual response (V0)
        P<.001.
        Bilateral optic nerve damage; Terson’s syndrome; Cortical blindness
        Consistent command following (A4)
        P<.001.
        No motor response (M0)
        P<.001.
        Quadriplegia
        No visual response (V0)
        P<.001.
        Functional communication (C2)
        P<.001.
        Bilateral optic nerve damage; Terson’s syndrome; Cortical blindness
        Blink to threat (V1)
        P<.001.
        Functional communication (C2)
        P<.001.
        Visual fixation (V2)
        P<.001.
        Functional communication (C2)
        P<.001.
        3rd and 4th cranial nerve palsy; Ocular apraxia; Visual agnosia
        Visual pursuit (V3)
        P<.001.
        Functional communication (C2)
        P<.001.
        Ocular apraxia; Visual agnosia
        Object recognition (V5)
        P<.001.
        No motor response (M0)
        P<.001.
        Quadriplegia
        No motor response (M0)
        P<.001.
        Functional communication (C2)
        P<.001.
        Abnormal posturing (M1)
        P<.001.
        Functional communication (C2)
        P<.001.
        Severe spasticity; Severe spasticity, hypertonus or hypotonus
        Flexion withdrawal (M2)
        P<.001.
        Functional communication (C2)
        P<.001.
        Localization to pain (M3)
        P<.001.
        Functional communication (C2)
        P<.001.
        Apraxia
        Object manipulation (M4)
        P<.001.
        Functional communication (C2)
        P<.001.
        Severe spasticity, hypertonus or hypotonus; Apraxia
        No verbal response (Ve0)
        P<.001.
        Functional communication (C2)
        P<.001.
        Facial nerve palsy/Oromotor weakness
        Oral reflexive movement (Ve1)
        P<.001.
        Functional communication (C2)
        P<.001.
        Vocalization (Ve2)
        P<.001.
        Functional communication (C2)
        P<.001.
        Functional communication (C2)
        P<.001.
        Eyes open with stimulation (Ar1)
        P<.001.
        N/A
        These combinations are clinically expected and likely to be improbable due to the population included in the sample (mainly VS/MCS patients).
        + Non-observed subscore combinations.
        P<.001.
        These combinations are clinically expected and likely to be improbable due to the population included in the sample (mainly VS/MCS patients).
        Awake with preserved vision but unable to open the eyelids.

        Supplemenatary Data

        Linked Article