This study examined aerobic capacity, upper leg muscular strength, and static postural control as correlates of the energetic cost of walking (Cw) in moderate multiple sclerosis (MS) mobility disability.
Persons (N=44) with MS (aged 48.43±8.64 years) who have reached a benchmark of moderate mobility disability (ie, Expanded Disability Status Scale scores between 4.0 and 6.0) participated in the study.
Main Outcome Measures
Cw was based on (1) net oxygen consumption collected using a portable metabolic unit and (2) walking speed during the 6-minute walk test. Participants underwent standard assessments of peak aerobic capacity, upper leg muscular strength, and static postural control.
The data were analyzed using bivariate correlation and linear regression analyses. Cw was inversely correlated with peak oxygen consumption (r=–.308, P<.05), peak power output (r=–.548, P<.00), and peak torque at 75° knee flexion (r=–.340, P<.05), whereas Cw was positively correlated center of pressure area sway (r=.319, P<.05), and mediolateral sway velocity (r=.411, P<.05). 40.3% of variance in Cw was explained by peak power output (β=–.526, P<.01) and mediolateral sway velocity (β=.339, P<.05).
Our findings demonstrate that aerobic power and postural sway may be important correlates of Cw in moderate MS mobility disability. Peak power output reflects a person’s physiological functional reserve that is directly relevant for understanding the penalty of walking impairment on the energetic demands of walking. The association between mediolateral postural sway and Cw suggests that mechanical inefficiency controlling the trajectory of the body’s center of pressure during ambulation may contribute to the elevated Cw.
List of abbreviations:6MWT (6-Minute Walk test), COP (center of pressure), Cw (energetic cost of walking), EDSS (Expanded Disability Status Scale), MS (multiple sclerosis), PDDS (Patient Determined Disease Steps), V.o2 (oxygen consumption per unit time), Vo2peak (peak oxygen consumption)
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Published online: July 03, 2018
© 2018 by the American Congress of Rehabilitation Medicine