There is a growing interest in individual response differences and exploring potential
predictors of these individual responses. The recent study by Layne et al
1
was a secondary analysis of data from the Lifestyle Interventions and Independence
for Elders study,
2
and focused on individual differences in response to the physical activity intervention
that was implemented. The primary outcomes were physical function (gait speed over
400m) and lower extremity function assessed at baseline and 6, 12, and 24 months.
Participants were randomized to an intervention group (n=818) involving a moderate-intensity
physical activity program, or a comparator group (n=817) involving monthly workshops
covering relevant health information. We have some comments and questions regarding
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References
- Predictors of change in physical function in older adults in response to long-term, structured physical activity: the LIFE study.Arch Phys Med Rehabil. 2017; 98: 11-24.e3
- Effect of structured physical activity on prevention of major mobility disability in older adults: the LIFE study randomized clinical trial.JAMA. 2014; 311: 2387-2396
- True and false interindividual differences in the physiological response to an intervention.Exp Physiol. 2015; 100: 577-588
- Blood pressure status and post-exercise hypotension: an example of a spurious correlation in hypertension research?.J Hum Hypertens. 2010; 24: 585-592
Article info
Footnotes
Disclosures: none.
Identification
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© 2017 by the American Congress of Rehabilitation Medicine
