Advertisement
Review article (meta-analysis)| Volume 99, ISSUE 8, P1660-1680.e21, August 2018

Effectiveness of Surgical and Postsurgical Interventions for Carpal Tunnel Syndrome—A Systematic Review

      Abstract

      Objective

      To present an evidence-based overview of the effectiveness of surgical and postsurgical interventions for carpal tunnel syndrome (CTS).

      Data Sources

      The Cochrane Library, PubMed, EMBASE, CINAHL, and PEDro were searched for relevant systematic reviews and randomized controlled trials (RCTs) up to April 8, 2016.

      Study Selection

      Two reviewers independently applied the inclusion criteria to select potential studies.

      Data Extraction

      Two reviewers independently extracted the data and assessed the methodologic quality.

      Data Synthesis

      A best-evidence synthesis was performed to summarize the results. Four systematic reviews and 33 RCTs were included. Surgery versus nonsurgical interventions, timing of surgery, and various surgical techniques and postoperative interventions were studied. Corticosteroid injection was more effective than surgery (strong evidence, short-term). Surgery was more effective than splinting or anti-inflammatory drugs plus hand therapy (moderate evidence, midterm and long-term). Manual therapy was more effective than surgical treatment (moderate evidence, short-term and midterm). Within surgery, corticosteroid irrigation of the median nerve before skin closure as additive to CTS release or the direct vision plus tunneling technique was more effective than standard open CTS release (moderate evidence, short-term). Furthermore, short was more effective than long bulky dressings, and a sensory retraining program was more effective than no program after surgery (moderate evidence, short-term). For all other interventions only conflicting, limited, or no evidence was found.

      Conclusions

      Surgical treatment seems to be more effective than splinting or anti-inflammatory drugs plus hand therapy in the short-term, midterm, and/or long-term to treat CTS. However there is strong evidence that a local corticosteroid injection is more effective than surgery in the short-term, and moderate evidence that manual therapy is more effective than surgery in the short-term and midterm. There is no unequivocal evidence that suggests one surgical treatment is more effective than the other. Postsurgical, a short- (2-3 days) favored a long-duration (9-14 days) bulky dressing and a sensory retraining program seems to be more effective than no program in short-term. More research regarding the optimal timing of surgery for CTS is needed.

      Keywords

      List of abbreviations:

      CI (confidence interval), CTS (carpal tunnel syndrome), MD (mean difference), RCT (randomized controlled trial), RR (relative risk), SMD (standardized mean difference)
      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'

      Subscribe:

      Subscribe to Archives of Physical Medicine and Rehabilitation
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect

      References

        • de Krom M.C.
        • Knipschild P.G.
        • Kester A.D.
        • Thijs C.T.
        • Boekkooi P.F.
        • Spaans F.
        Carpal tunnel syndrome: prevalence in the general population.
        J Clin Epidemiol. 1992; 45: 373-376
        • Huisstede B.M.
        • Miedema H.S.
        • Verhagen A.P.
        • Koes B.W.
        • Verhaar J.A.
        Multidisciplinary consensus on the terminology and classification of complaints of the arm, neck and/or shoulder.
        Occup Environ Med. 2007; 64: 313-319
        • van Rijn R.M.
        • Huisstede B.M.
        • Koes B.W.
        • Burdorf A.
        Associations between work-related factors and the carpal tunnel syndrome—a systematic review.
        Scand J Work Environ Health. 2009; 35: 19-36
        • de Krom M.C.
        • van Croonenborg J.J.
        • Blaauw G.
        • Scholten R.J.
        • Spaans F.
        [Guideline ‘Diagnosis and treatment of carpal tunnel syndrome’].
        Ned Tijdschr Geneeskd. 2008; 152 ([Dutch]): 76-81
        • Huisstede B.M.
        • Hoogvliet P.
        • Randsdorp M.S.
        • Glerum S.
        • Van Middelkoop M.
        • Koes B.W.
        Carpal tunnel syndrome. Part I: effectiveness of conservative treatments—a systematic review.
        Arch Phys Med Rehabil. 2010; 91: 981-1004
        • Huisstede B.M.
        • Friden J.
        • Coert J.H.
        • Hoogvliet P.
        • European H.G.
        Carpal tunnel syndrome: hand surgeons, hand therapists, and physical medicine and rehabilitation physicians agree on a multidisciplinary treatment guideline—results from the European HANDGUIDE Study.
        Arch Phys Med Rehabil. 2014; 95: 2253-2263
        • Verdugo R.J.
        • Salinas R.A.
        • Castillo J.L.
        • Cea J.G.
        Surgical versus non-surgical treatment for carpal tunnel syndrome.
        Cochrane Database Syst Rev. 2008; : CD001552
        • Graham B.
        • Peljovich A.E.
        • Afra R.
        • et al.
        The American Academy of Orthopaedic Surgeons evidence-based clinical practice guideline on: management of carpal tunnel syndrome.
        J Bone Joint Surg Am. 2016; 98: 1750-1754
        • Aroori S.
        • Spence R.A.
        Carpal tunnel syndrome.
        Ulster Med J. 2008; 77: 6-17
        • Agee J.M.
        • McCarroll Jr., H.R.
        • Tortosa R.D.
        • Berry D.A.
        • Szabo R.M.
        • Peimer C.A.
        Endoscopic release of the carpal tunnel: a randomized prospective multicenter study.
        J Hand Surg Am. 1992; 17: 987-995
        • Agee J.M.
        • McCarroll H.R.
        • North E.R.
        Endoscopic carpal tunnel release using the single proximal incision technique.
        Hand Clin. 1994; 10: 647-659
        • Chow J.C.
        Endoscopic release of the carpal ligament: a new technique for carpal tunnel syndrome.
        Arthroscopy. 1989; 5: 19-24
        • Chow J.C.
        The Chow technique of endoscopic release of the carpal ligament for carpal tunnel syndrome: four years of clinical results.
        Arthroscopy. 1993; 9: 301-314
        • Vasiliadis H.S.
        • Georgoulas P.
        • Shrier I.
        • Salanti G.
        • Scholten R.J.
        Endoscopic release for carpal tunnel syndrome.
        Cochrane Database Syst Rev. 2014; : CD008265
        • Bland J.D.
        Carpal tunnel syndrome.
        BMJ. 2007; 335: 343-346
        • Scholten R.J.
        • Mink van der Molen A.
        • Uitdehaag B.M.
        • Bouter L.M.
        • de Vet H.C.
        Surgical treatment options for carpal tunnel syndrome.
        Cochrane Database Syst Rev. 2007; : CD003905
        • Peters S.
        • Page M.J.
        • Coppieters M.W.
        • Ross M.
        • Johnston V.
        Rehabilitation following carpal tunnel release.
        Cochrane Database Syst Rev. 2016; 2: CD004158
        • Huisstede B.M.
        • Randsdorp M.S.
        • Coert J.
        • Glerum S.
        • van Middelkoop M.
        • Koes B.W.
        Carpal tunnel syndrome. Part II: effectiveness of surgical treatments—a systematic review.
        Arch Phys Med Rehabil. 2010; 91: 1005-1024
        • Furlan A.D.
        • Pennick V.
        • Bombardier C.
        • van Tulder M.
        2009 updated method guidelines for systematic reviews in the Cochrane Back Review Group.
        Spine (Phila Pa 1976). 2009; 34: 1929-1941
        • van Tulder M.
        • Furlan A.
        • Bombardier C.
        • Bouter L.
        Updated method guidelines for systematic reviews in the Cochrane Collaboration Back Review Group.
        Spine. 2003; 28: 1290-1299
        • Chen L.
        • Duan X.
        • Huang X.
        • Lv J.
        • Peng K.
        • Xiang Z.
        Effectiveness and safety of endoscopic versus open carpal tunnel decompression.
        Arch Orthop Trauma Surg. 2014; 134: 585-593
        • Aslani H.R.
        • Alizadeh K.
        • Eajazi A.
        • et al.
        Comparison of carpal tunnel release with three different techniques.
        Clin Neurol Neurosurg. 2012; 114: 965-968
        • Ejiri S.
        • Kikuchi S.
        • Maruya M.
        • Sekiguchi Y.
        • Kawakami R.
        • Konno S.
        Short-term results of endoscopic (Okutsu method) versus palmar incision open carpal tunnel release: a prospective randomized controlled trial.
        Fukushima J Med Sci. 2012; 58: 49-59
        • Kang H.J.
        • Koh I.H.
        • Lee T.J.
        • Choi Y.R.
        Endoscopic carpal tunnel release is preferred over mini-open despite similar outcome: a randomized trial.
        Clin Orthop Relat Res. 2013; 471: 1548-1554
        • Ucan H.
        • Yagci I.
        • Yilmaz L.
        • Yagnurku F.
        • Keskin D.
        • Bodur H.
        Comparison of splinting, splinting plus local steroid injection and open carpal tunnel release outcomes in idiopathic carpal tunnel syndrome.
        Rheumatol Int. 2006; 27: 45-51
        • Crnkovic T.
        • Bilic R.
        • Trkulja V.
        • Cesarik M.
        • Gotovac N.
        • Kolundzic R.
        The effect of epineurotomy on the median nerve volume after the carpal tunnel release: a prospective randomised double-blind controlled trial.
        Int Orthop. 2012; 36: 1885-1892
        • Padua R.
        • Padua L.
        • Bondi R.
        • Campi A.
        • Ceccarelli E.
        • Padua S.
        Intrasurgical use of steroids on carpal tunnel syndrome: a randomized, prospective, double-blind controlled study.
        J Orthop Traumatol. 2003; 4: 76-80
        • Suppaphol S.
        • Worathanarat P.
        • Kawinwongkovit V.
        • Pittayawutwinit P.
        The comparison between limited open carpal tunnel release using direct vision and tunneling technique and standard open carpal tunnel release: a randomized controlled trial study.
        J Med Assoc Thai. 2012; 95: 532-536
        • Fernández-de-Las Peñas C.
        • Ortega-Santiago R.
        • de la Llave-Rincon A.I.
        • et al.
        Manual physical therapy versus surgery for carpal tunnel syndrome: a randomized parallel-group trial.
        J Pain. 2015; 16: 1087-1094
        • Jarvik J.G.
        • Comstock B.A.
        • Kliot M.
        • et al.
        Surgery versus non-surgical therapy for carpal tunnel syndrome: a randomised parallel-group trial.
        Lancet. 2009; 374: 1074-1081
        • Atroshi I.
        • Hofer M.
        • Larsson G.U.
        • Ranstam J.
        Extended follow-up of a randomized clinical trial of open vs endoscopic release surgery for carpal tunnel syndrome.
        JAMA. 2015; 314: 1399-1401
        • Cho Y.J.
        • Lee J.H.
        • Shin D.J.
        • Park K.H.
        Comparison of short wrist transverse open and limited open techniques for carpal tunnel release: a randomized controlled trial of two incisions.
        J Hand Surg Eur Vol. 2016; 41: 143-147
        • Shalimar A.
        • Nor-Hazla M.H.
        • Arifaizad A.
        • Jamari S.
        Splinting after carpal tunnel release: does it really matter?.
        Malays Orthop J. 2015; 9: 41-46
        • Gumustas S.A.
        • Ekmekci B.
        • Tosun H.B.
        • Orak M.M.
        • Bekler H.I.
        Similar effectiveness of the open versus endoscopic technique for carpal tunnel syndrome: a prospective randomized trial.
        Eur J Orthop Surg Traumatol. 2015; 25: 1253-1260
        • Ullah I.
        Local steroid injection or carpal tunnel release for carpal tunnel syndrome—which is more effective?.
        J Postgrad Med Inst. 2013; 27: 194-199
        • Ly-Pen D.
        • Andreu J.L.
        • de Blas G.
        • Sanchez-Olaso A.
        • Millan I.
        Surgical decompression versus local steroid injection in carpal tunnel syndrome: a one-year, prospective, randomized, open, controlled clinical trial.
        Arthritis Rheum. 2005; 52: 612-619
        • Siegmeth A.W.
        • Hopkinson-Woolley J.A.
        Standard open decompression in carpal tunnel syndrome compared with a modified open technique preserving the superficial skin nerves: a prospective randomized study.
        J Hand Surg Am. 2006; 31: 1483-1489
        • Chandra P.S.
        • Singh P.K.
        • Goyal V.
        • Chauhan A.K.
        • Thakkur N.
        • Tripathi M.
        Early versus delayed endoscopic surgery for carpal tunnel syndrome: prospective randomized study.
        World Neurosurg. 2013; 79: 767-772
        • Elsharif M.
        • Papanna M.
        • Helm R.
        Long-term follow up outcome results of Knifelight carpal tunnel release and conventional open release following a departmental randomized controlled trial. A prospective study.
        Pol Orthop Traumatol. 2014; 79: 67-70
        • Forward D.P.
        • Singh A.K.
        • Lawrence T.M.
        • Sithole J.S.
        • Davis T.R.
        • Oni J.A.
        Preservation of the ulnar bursa within the carpal tunnel: does it improve the outcome of carpal tunnel surgery? A randomized, controlled trial.
        J Bone Joint Surg Am. 2006; 88: 2432-2438
        • Tarallo M.
        • Fino P.
        • Sorvillo V.
        • Parisi P.
        • Scuderi N.
        Comparative analysis between minimal access versus traditional accesses in carpal tunnel syndrome: a perspective randomised study.
        J Plast Reconstr Aesthet Surg. 2014; 67: 237-243
        • Acar M.A.
        • Kutahya H.
        • Gulec A.
        • Elmadag M.
        • Karalezli N.
        • Ogun T.C.
        Triggering of the digits after carpal tunnel surgery.
        Ann Plast Surg. 2015; 75: 393-397
        • Castillo T.N.
        • Yao J.
        Prospective randomized comparison of single-incision and two-incision carpal tunnel release outcomes.
        Hand (N Y). 2014; 9: 36-42
        • Hamed A.R.
        • Makki D.
        • Chari R.
        • Packer G.
        Double- versus single-incision technique for open carpal tunnel release.
        Orthopedics. 2009; 32
        • Larsen M.B.
        • Sorensen A.I.
        • Crone K.L.
        • Weis T.
        • Boeckstyns M.E.
        Carpal tunnel release: a randomized comparison of three surgical methods.
        J Hand Surg Eur Vol. 2013; 38: 646-650
        • Cresswell T.R.
        • Heras-Palou C.
        • Bradley M.J.
        • et al.
        Long-term outcome after carpal tunnel decompression—a prospective randomised study of the Indiana Tome and a standard limited palmar incision.
        J Hand Surg Eur Vol. 2008; 33: 332-336
        • Michelotti B.
        • Romanowsky D.
        • Hauck R.M.
        Prospective, randomized evaluation of endoscopic versus open carpal tunnel release in bilateral carpal tunnel syndrome: an interim analysis.
        Ann Plast Surg. 2014; 73: S157-S160
        • Vanni D.
        • Sirabella F.S.
        • Galzio R.
        • Salini V.
        • Magliani V.
        The double tunnels technique: an alternative minimally invasive approach for carpal tunnel syndrome.
        J Neurosurg. 2015; 123: 1230-1237
        • Andreu J.L.
        • Ly-Pen D.
        • Millan I.
        • de Blas G.
        • Sanchez-Olaso A.
        Local injection versus surgery in carpal tunnel syndrome: neurophysiologic outcomes of a randomized clinical trial.
        Clin Neurophysiol. 2014; 125: 1479-1484
        • Heidarian A.
        • Abbasi H.
        • Hasanzadeh Hoseinabadi M.
        • Hajialibeyg A.
        • Kalantar Motamedi S.M.
        • Seifirad S.
        Comparison of Knifelight surgery versus conventional open surgery in the treatment of carpal tunnel syndrome.
        Iran Red Crescent Med J. 2013; 15: 385-388
        • Stepic N.
        • Novakovic M.
        • Martic V.
        • Peric D.
        Effects of perineural steroid injections on median nerve conduction during the carpal tunnel release.
        Vojnosanit Pregl. 2008; 65: 825-829
        • Ucar B.Y.
        • Demirtas A.
        • Bulut M.
        • Azboy I.
        • Ucar D.
        Carpal tunnel decompression: two different mini-incision techniques.
        Eur Rev Med Pharmacol Sci. 2012; 16: 533-538
        • Xu L.
        • Huang F.
        • Hou C.
        Treatment for carpal tunnel syndrome by coronal Z-type lengthening of the transverse carpal ligament.
        J Pak Med Assoc. 2011; 61: 1068-1071
        • Zhang X.
        • Li Y.
        • Wen S.
        • Zhu H.
        • Shao X.
        • Yu Y.
        Carpal tunnel release with subneural reconstruction of the transverse carpal ligament compared with isolated open and endoscopic release.
        Bone Joint J. 2015; 97-B: 221-228
        • Atroshi I.
        • Larsson G.U.
        • Ornstein E.
        • Hofer M.
        • Johnsson R.
        • Ranstam J.
        Outcomes of endoscopic surgery compared with open surgery for carpal tunnel syndrome among employed patients: randomised controlled trial.
        BMJ. 2006; 332: 1473
        • Tuzuner S.
        • Inceoglu S.
        • Bilen F.E.
        Median nerve excursion in response to wrist movement after endoscopic and open carpal tunnel release.
        J Hand Surg Am. 2008; 33: 1063-1068
        • Hoefnagels W.A.
        • van Kleef J.G.
        • Mastenbroek G.G.
        • de Blok J.A.
        • Breukelman A.J.
        • de Krom M.C.
        [Surgical treatment of carpal tunnel syndrome: endoscopic or classical (open)? A prospective randomized trial].
        Ned Tijdschr Geneeskd. 1997; 141 ([Dutch]): 878-882
        • Saw N.L.
        • Jones S.
        • Shepstone L.
        • Meyer M.
        • Chapman P.G.
        • Logan A.M.
        Early outcome and cost-effectiveness of endoscopic versus open carpal tunnel release: a randomized prospective trial.
        J Hand Surg Br. 2003; 28: 444-449
        • Sennwald G.R.
        • Benedetti R.
        The value of one-portal endoscopic carpal tunnel release: a prospective randomized study.
        Knee Surg Sports Traumatol Arthrosc. 1995; 3: 113-116
        • Brown R.A.
        • Gelberman R.H.
        • Seiler III, J.G.
        • et al.
        Carpal tunnel release. A prospective, randomized assessment of open and endoscopic methods.
        J Bone Joint Surg Am. 1993; 75: 1265-1275
        • Ferdinand R.D.
        • MacLean J.G.
        Endoscopic versus open carpal tunnel release in bilateral carpal tunnel syndrome. A prospective, randomised, blinded assessment.
        J Bone Joint Surg Br. 2002; 84: 375-379
        • Trumble T.E.
        • Diao E.
        • Abrams R.A.
        • Gilbert-Anderson M.M.
        Single-portal endoscopic carpal tunnel release compared with open release: a prospective, randomized trial.
        J Bone Joint Surg Am. 2002; 84: 1107-1115
        • Wong K.C.
        • Hung L.K.
        • Ho P.C.
        • Wong J.M.
        Carpal tunnel release. A prospective, randomised study of endoscopic versus limited-open methods.
        J Bone Joint Surg Br. 2003; 85: 863-868
        • Incoll I.W.
        • Bateman E.
        • Myers A.
        Endoscopic vs open carpal tunnel release.
        Orthopaedic Proceedings. 2004; 86B: 478
        • Jacobsen M.B.
        • Rahme H.
        A prospective, randomized study with an independent observer comparing open carpal tunnel release with endoscopic carpal tunnel release.
        J Hand Surg Br. 1996; 21: 202-204
        • Macdermid J.C.
        • Richards R.S.
        • Roth J.H.
        • Ross D.C.
        • King G.J.
        Endoscopic versus open carpal tunnel release: a randomized trial.
        J Hand Surg Am. 2003; 28: 475-480
        • Malhotra R.
        • Kiran E.K.
        • Dua A.
        • Mallinath S.G.
        • Bhan S.
        Endoscopic versus open carpal tunnel release: a short-term comparative study.
        Indian J Orthop. 2007; 41: 57-61
        • Rab M.
        • Grunbeck M.
        • Beck H.
        • et al.
        Intra-individual comparison between open and 2-portal endoscopic release in clinically matched bilateral carpal syndrome.
        J Plast Reconstr Aesthet Surg. 2006; 59: 730-736
        • Schafer W.
        • Sander K.E.
        • Walter A.
        • Weitbrecht W.U.
        [Agee endoscopic operation of carpal tunnel syndrome in comparison with open surgical technique].
        Handchir Mikrochir Plast Chir. 1996; 28 ([German]): 143-146
        • Stark B.
        • Engkvist-Lofmark C.
        [Endoscopic operation or conventional open surgical technique in carpal tunnel syndrome: a prospective comparative study].
        Handchir Mikrochir Plast Chir. 1996; 28 ([German]): 128-132
        • Dumontier C.
        • Sokolow C.
        • Leclercq C.
        • Chauvin P.
        Early results of conventional versus two-portal endoscopic carpal tunnel release. A prospective study.
        J Hand Surg Br. 1995; 20: 658-662
        • Eichhorn J.
        • Dieterich K.
        Open versus endoscopic carpal tunnel release. Results of a prospective study.
        Chirurgische Praxis. 2003; 61: 279-283
        • Erdmann M.W.
        Endoscopic carpal tunnel decompression.
        J Hand Surg Br. 1994; 19: 5-13
        • Foucher G.
        • Buch N.
        • Van Overstraeten L.
        • Gautherie M.
        • Jesel M.
        [Carpal tunnel syndrome. Can it still be a controversial topic?].
        Chirurgie. 1993; 119 ([French]): 80-84
        • Giele H.
        Bilateral simultaneous carpal tunnel release to prospectively compare endoscopic and open techniques.
        J Hand Surg Br. 2000; ([abstract no. 36]): 28-29
        • Koskella K.R.
        • Alexander C.
        A comparison between open and endoscopic carpal tunnel release.
        Orthop Trans. 1996; 20: 1102
        • Mackenzie D.J.
        • Hainer R.
        • Wheatley M.J.
        Early recovery after endoscopic vs. short-incision open carpal tunnel release.
        Ann Plast Surg. 2000; 44: 601-604
        • Sørensen A.I.
        • Boeckstyns M.E.
        • Nielsen N.S.
        • Haugegard M.
        Carpal tunnel release, a comparison of 3 methods—a preliminary report.
        Acta Orthop Scand. 1997; 68: 24-25
        • Tian Y.
        • Zhao H.
        • Wang T.
        Prospective comparison of endoscopic and open surgical methods for carpal tunnel syndrome.
        Chin Med Sci J. 2007; 22: 104-107
        • Werber K.D.
        • Braver R.B.
        • Richtarsky I.
        Endoscopic carpal tunnel release versus open procedure: a prospective randomized study.
        Journal of Hand Surgery (European Volume). 1996; 21B: 11-12
        • Westphal K.
        • Bayat M.
        • Wustner-Hofmann M.
        • Hofmann A.
        Course of clinical symptoms before and after surgical decompression in carpal tunnel surgery [in German].
        Lymphologie in Forschung Und Praxis. 2000; 4: 69-73
      1. Higgins JPT, Altman DG, Sterne JAC (editors). Chapter 8: Assessing risk of bias in included studies. In: Higgins JPT, Green S (editors). Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0 (updated March 2011). The Cochrane Collaboration, 2011. Available at: www.cochrane-handbook.org. Accessed June 26, 2017.

        • Leinberry C.F.
        • Hammond III, N.L.
        • Siegfried J.W.
        The role of epineurotomy in the operative treatment of carpal tunnel syndrome.
        J Bone Joint Surg Am. 1997; 79: 555-557
        • Mackinnon S.E.
        • McCabe S.
        • Murray J.F.
        • et al.
        Internal neurolysis fails to improve the results of primary carpal tunnel decompression.
        J Hand Surg Am. 1991; 16: 211-218
        • Jugovac I.
        • Burgic N.
        • Micovic V.
        • et al.
        Carpal tunnel release by limited palmar incision vs traditional open technique: randomized controlled trial.
        Croat Med J. 2002; 43: 33-36
        • Lowry Jr., W.E.
        • Follender A.B.
        Interfascicular neurolysis in the severe carpal tunnel syndrome. A prospective, randomized, double-blind, controlled study.
        Clin Orthop Relat Res. 1988; 227: 251-254
        • Bhattacharya R.
        • Birdsall P.D.
        • Finn P.
        • Stothard J.
        A randomized controlled trial of knifelight and open carpal tunnel release.
        J Hand Surg Br. 2004; 29: 113-115
        • Helm R.H.
        • Vaziri S.
        Evaluation of carpal tunnel release using the Knifelight instrument.
        J Hand Surg Br. 2003; 28: 251-254
        • Shum C.
        • Parisien M.
        • Strauch R.J.
        • Rosenwasser M.P.
        The role of flexor tenosynovectomy in the operative treatment of carpal tunnel syndrome.
        J Bone Joint Surg Am. 2002; 84: 221-225
        • Gerritsen A.A.
        • de Vet H.C.
        • Scholten R.J.
        • Bertelsmann F.W.
        • de Krom M.C.
        • Bouter L.M.
        Splinting vs surgery in the treatment of carpal tunnel syndrome: a randomized controlled trial.
        JAMA. 2002; 288: 1245-1251
        • Hui A.C.
        • Wong S.
        • Leung C.H.
        • et al.
        A randomized controlled trial of surgery vs steroid injection for carpal tunnel syndrome.
        Neurology. 2005; 64: 2074-2078
        • Garland H.
        • Langworth E.P.
        • Taverner D.
        • Clark J.M.
        Surgical treatment for the carpal tunnel syndrome.
        Lancet. 1964; 1: 1129-1130
        • Schulz K.F.C.I.
        • Hayes R.J.
        • Altman D.G.
        Empirical evidence of bias. Dimensions of methodological quality associated with estimates of treatment effects in controlled trials.
        JAMA. 1995; 273: 408-412
        • Janssen R.G.
        • Schwartz D.A.
        • Velleman P.F.
        A randomized controlled study of contrast baths on patients with carpal tunnel syndrome.
        J Hand Ther. 2009; 22 (quiz 208): 200-207
        • Jeffrey S.L.
        • Belcher H.J.
        Use of arnica to relieve pain after carpal-tunnel release surgery.
        Altern Ther Health Med. 2002; 8: 66-68
        • Jerosch-Herold C.
        • Shepstone L.
        • Miller L.
        Sensory relearning after surgical treatment for carpal tunnel syndrome: a pilot clinical trial.
        Muscle Nerve. 2012; 46: 885-890
        • Pomerance J.
        • Fine I.
        Outcomes of carpal tunnel surgery with and without supervised postoperative therapy.
        J Hand Surg Am. 2007; 32 (discussion 1164-1165): 1159-1163
        • Sawan S.A.
        • Sayed Mahmoud H.M.
        • Hussien M.M.
        Effect of different physical therapy modalities on post-operative recovery following transverse carpal ligament release: a randomized controlled trial.
        Physiotherapy Pract Res. 2013; 34: 75-82
        • Stevinson C.
        • Devaraj V.S.
        • Fountain-Barber A.
        • Hawkins S.
        • Ernst E.
        Homeopathic arnica for prevention of pain and bruising: randomized placebo-controlled trial in hand surgery.
        J R Soc Med. 2003; 96: 60-65
        • Williams A.M.
        • Baker P.A.
        • Platt A.J.
        The impact of dressings on recovery from carpal tunnel decompression.
        J Plast Reconstr Aesthet Surg. 2008; 61: 1493-1495
        • Alves M.P.
        • Araujo G.C.
        Low-level laser therapy after carpal tunnel release.
        Rev Bras Ortop. 2011; 46: 697-701
        • Hochberg J.
        A randomized prospective study to assess the efficacy of two cold-therapy treatments following carpal tunnel release.
        J Hand Ther. 2001; 14: 208-215
        • Martins R.S.
        • Siqueira M.G.
        • Simplicio H.
        Wrist immobilization after carpal tunnel release: a prospective study.
        Arq Neuropsiquiatr. 2006; 64: 596-599
        • Ritting A.W.
        • Leger R.
        • O'Malley M.P.
        • Mogielnicki H.
        • Tucker R.
        • Rodner C.M.
        Duration of postoperative dressing after mini-open carpal tunnel release: a prospective, randomized trial.
        J Hand Surg Am. 2012; 37: 3-8
        • Gordon T.
        • Amirjani N.
        • Edwards D.C.
        • Chan K.M.
        Brief post-surgical electrical stimulation accelerates axon regeneration and muscle reinnervation without affecting the functional measures in carpal tunnel syndrome patients.
        Exp Neurol. 2010; 223: 192-202
        • Cebesoy O.
        • Kose K.C.
        • Kuru I.
        • Altinel L.
        • Gul R.
        • Demirtas M.
        Use of a splint following open carpal tunnel release: a comparative study.
        Adv Ther. 2007; 24: 478-484
        • Fagan D.J.
        • Evans A.
        • Ghandour A.
        • Prabhkaran P.
        • Clay N.R.
        A controlled clinical trial of postoperative hand elevation at home following day-case surgery.
        J Hand Surg Br. 2004; 29: 458-460
        • Bhatia R.
        • Field J.
        • Grote J.
        • Huma H.
        Does splintage help pain after carpal tunnel release?.
        J Hand Surg Br. 2000; 25: 150
        • Li G.F.
        • Tian D.H.
        • Yu J.L.
        • Li W.Z.
        • Meng J.
        Synergistic effects of compound physical factor treatment on neurological outcome after peripheral nerve entrapment surgery—a randomized controlled study.
        Neural Regen Res. 2008; 3: 97-100
        • Bury T.F.
        • Akelman E.
        • Weiss A.P.
        Prospective, randomized trial of splinting after carpal tunnel release.
        Ann Plast Surg. 1995; 35: 19-22
        • Huemer G.M.
        • Koller M.
        • Pachinger T.
        • Dunst K.M.
        • Schwarz B.
        • Hintringer T.
        Postoperative splinting after open carpal tunnel release does not improve functional and neurological outcome.
        Muscle Nerve. 2007; 36: 528-531
        • Provinciali L.
        • Giattini A.
        • Splendiani G.
        • Logullo F.
        Usefulness of hand rehabilitation after carpal tunnel surgery.
        Muscle Nerve. 2000; 23: 211-216
        • Cook A.C.
        • Szabo R.M.
        • Birkholz S.W.
        • King E.F.
        Early mobilization following carpal tunnel release. A prospective randomized study.
        J Hand Surg Br. 1995; 20: 228-230
        • Finsen V.
        • Andersen K.
        • Russwurm H.
        No advantage from splinting the wrist after open carpal tunnel release. A randomized study of 82 wrists.
        Acta Orthop Scand. 1999; 70: 288-292
        • Ly-Pen D.
        • Andreu J.L.
        • Millan I.
        • de Blas G.
        • Sanchez-Olaso A.
        Comparison of surgical decompression and local steroid injection in the treatment of carpal tunnel syndrome: 2-year clinical results from a randomized trial.
        Rheumatology (Oxford). 2012; 51: 1447-1454
        • Cellocco P.
        • Rossi C.
        • Bizzarri F.
        • Patrizio L.
        • Costanzo G.
        Mini-open blind procedure versus limited open technique for carpal tunnel release: a 30-month follow-up study.
        J Hand Surg Am. 2005; 30: 493-499
        • Cellocco P.
        • Rossi C.
        • El Boustany S.
        • Di Tanna G.L.
        • Costanzo G.
        Minimally invasive carpal tunnel release.
        Orthop Clin North Am. 2009; 40 (vii): 441-448
        • Brüser P.
        • Richter M.
        • Larkin G.
        • Lefering R.
        The operative treatment of carpal tunnel syndrome and its relevance to endoscopic release.
        Eur J Plast Surg. 1999; 22: 80-84
        • Citron N.D.
        • Bendall S.P.
        Local symptoms after open carpal tunnel release. A randomized prospective trial of two incisions.
        J Hand Surg Br. 1997; 22: 317-321
        • Nakamichi K.
        • Tachibana S.
        Ultrasonographically assisted carpal tunnel release.
        J Hand Surg Am. 1997; 22: 853-862
        • Nitzsche T.
        • Steen M.
        Open and modified open surgery technique to split the retinaculum flexorum in treatment of carpal tunnel syndrome [in German].
        Deutsche Gesellschaft Fur Chirurgie. 1999; : 999-1001
        • Richter V.M.
        • Bruser P.
        [Surgical treatment of carpal tunnel syndrome: a comparison between long and short incision and endoscopic release].
        Handchir Mikrochir Plast Chir. 1996; 28 ([German]): 160-166
        • Dias J.J.
        • Bhowal B.
        • Wildin C.J.
        • Thompson J.R.
        Carpal tunnel decompression. Is lengthening of the flexor retinaculum better than simple division?.
        J Hand Surg Br. 2004; 29: 271-276
        • Duncan K.H.
        • Lewis Jr., R.C.
        • Foreman K.A.
        • Nordyke M.D.
        Treatment of carpal tunnel syndrome by members of the American Society for Surgery of the Hand: results of a questionnaire.
        J Hand Surg Am. 1987; 12: 384-391

      Linked Article

      • Correction
        Archives of Physical Medicine and RehabilitationVol. 101Issue 9
        • Preview
          In the article by Huisstede et al, Effectiveness of Surgical and Postsurgical Interventions for Carpal Tunnel Syndrome - A Systematic Review, published in the Archives of Physical Medicine and Rehabilitation 2018; 99 : 1660-1680 https:// www.archives-pmr.org/article/S0003-9993(17 )30372-6/fulltext, the cited paper by Vanni et al, The double tunnels technique: an alternative minimally invasive approach for carpal tunnel syndrome published in J Neurosurg 2015;123:1230-7 was erroneously interpreted. This study compares two surgical procedures for carpal tunnel syndrome, the aforementioned double tunnels technique and a standard open decompression of the median nerve.
        • Full-Text
        • PDF