Abstract
Objectives
To determine whether objective (neuropsychological tests) and subjective measures
(questionnaires) of executive functions (EFs) are associated in patients with Parkinson
disease (PD), and to determine to what extent level of participation and quality of
life (QoL) of patients with PD can be predicted by these measures of EFs.
Design
Correlational research design (case-control and prediction design).
Setting
Departments of neuropsychology of 3 medical centers.
Participants
A sample (N=136) of patients with PD (n=42) and their relatives, and controls without
PD (n=94).
Interventions
Not applicable.
Main Outcome Measures
A test battery measuring EFs. In addition, patients, their relatives, and controls
completed the Dysexecutive Questionnaire, Brock Adaptive Functioning Questionnaire,
and Barkley Deficits in Executive Functioning Scale – time management questionnaires
measuring complaints about EFs. Participation and QoL were measured with the Impact
on Participation and Autonomy scale and the Parkinson's Disease Questionnaire-39,
respectively.
Results
Patients with PD showed impairments in EFs on objective tests and reported significantly
more complaints about EFs than did controls without PD. No associations were found
between patients' performances on objective and subjective measures of EFs. However,
both objective and subjective measures predicted patients' level of participation.
In addition, subjective measures of EFs predicted QoL in patients with PD.
Conclusions
These findings show that objective and subjective measures of EFs are not interchangeable
and that both approaches predict level of participation and QoL in patients with PD.
However, within this context, sex needs to be taken into account.
Keywords
List of abbreviations:
BADS (Behavioural Assessment of the Dysexecutive Syndrome), BAFQ (Brock Adaptive Functioning Questionnaire), BDEFS (Barkley Deficits in Executive Functioning Scale), DEX (Dysexecutive Questionnaire), EF (executive functions), HADS (Hospital Anxiety and Depression Scale), IPA (Impact on Participation and Autonomy), PD (Parkinson disease), PDQ-39 (Parkinson's Disease Questionnaire-39), QoL (quality of life)To read this article in full you will need to make a payment
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Article info
Publication history
Published online: April 17, 2017
Footnotes
Supported by the Netherlands Organisation for Scientific Research (NWO), the National Initiative Brain & Cognition (grant no. 056-11-012). This quick-result project is embedded in the pillar “The Healthy Brain, Program Cognitive Rehabilitation.”
Clinical Trial Registration No.: ISRCTN13595005.
Disclosures: none.
Identification
Copyright
© 2017 by the American Congress of Rehabilitation Medicine
