Advertisement

Association Between 7 Days Per Week Rehabilitation and Functional Recovery of Patients With Acute Stroke: A Retrospective Cohort Study Based on the Japan Rehabilitation Database

Published:December 12, 2016DOI:https://doi.org/10.1016/j.apmr.2016.11.004

      Abstract

      Objective

      To test the hypothesis that functional outcome of patients with stroke who receive 7d/wk of rehabilitation is generally better than that of similar patients who undergo 5 or 6d/wk of rehabilitation.

      Design

      Retrospective cohort study.

      Setting

      Acute hospitals.

      Participants

      From the Japan Rehabilitation Database, which includes data on 8033 patients with acute stroke collected between January 2005 and December 2013, we included 3072 patients with stroke who were admitted to the acute hospitals and received 7d/wk of rehabilitation.

      Intervention

      Seven days per week of rehabilitation was defined as rehabilitation therapy administrated by a physical or occupational therapist on every weekday, Saturday, and Sunday.

      Main Outcome Measure

      Favorable functional independence in daily living, defined as a modified Rankin Scale score of 0 to 2 at the time of discharge.

      Results

      A total of 1075 (35.0%) patients received 7d/wk of rehabilitation. Univariate analysis demonstrated a significant difference in favorable functional recovery between the 7d/wk rehabilitation group and non–7d/wk rehabilitation group (43.3% vs 37.6%, respectively; P=.002). Multivariate logistic regression analysis using the generalized estimating equations method showed that 7d/wk of rehabilitation was independently associated with favorable functional recovery.

      Conclusions

      Our cohort analysis demonstrated that 7d/wk of rehabilitation in early rehabilitation for patients with acute stroke can lead to functional recovery.

      Keywords

      List of abbreviations:

      LOS (length of stay), mRS (modified Rankin scale)
      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic and PersonalCorporate R&D Professionals
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'

      Subscribe:

      Subscribe to Archives of Physical Medicine and Rehabilitation
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect

      References

        • Biernaskie J.
        • Chernenko G.
        • Corbett D.
        Efficacy of rehabilitative experience declines with time after focal ischemic brain injury.
        J Neurosci. 2004; 24: 1245-1254
        • Liu N.
        • Cadilhac D.A.
        • Andrew N.E.
        • et al.
        Randomized controlled trial of early rehabilitation after intracerebral hemorrhage stroke: difference in outcomes within 6 months of stroke.
        Stroke. 2014; 45: 3502-3507
        • Winstein C.J.
        • Stein J.
        • Arena R.
        • et al.
        Guidelines for Adult Stroke Rehabilitation and Recovery: a guideline for healthcare professionals From the American Heart Association/American Stroke Association.
        Stroke. 2016; 47: e98-e169
        • Lohse K.R.
        • Lang C.E.
        • Boyd L.A.
        Is more better? Using metadata to explore dose-response relationships in stroke rehabilitation.
        Stroke. 2014; 45: 2053-2058
        • Peiris C.L.
        • Taylor N.F.
        • Shields N.
        Extra physical therapy reduces patient length of stay and improves functional outcomes and quality of life in people with acute or subacute conditions: a systematic review.
        Arch Phys Med Rehabil. 2011; 92: 1490-1500
        • Rapoport J.
        • Judd-Van Eerd M.
        Impact of physical therapy weekend coverage on length of stay in an acute care community hospital.
        Phys Ther. 1989; 69: 32-37
        • Ruff R.M.
        • Yarnell S.
        • Marinos J.M.
        Are stroke patients discharged sooner if in-patient rehabilitation services are provided seven v six days per week?.
        Am J Phys Med Rehabil. 1999; 78: 143-146
        • Brusco N.K.
        • Shields N.
        • Taylor N.F.
        • Paratz J.
        A Saturday physiotherapy service may decrease length of stay in patients undergoing rehabilitation in hospital: a randomised controlled trial.
        Aust J Physiother. 2007; 53: 75-81
        • DiSotto-Monastero M.
        • Chen X.
        • Fisch S.
        • Donaghy S.
        • Gomez M.
        Efficacy of 7 days per week inpatient admissions and rehabilitation therapy.
        Arch Phys Med Rehabil. 2012; 93: 2165-2169
        • Peiris C.L.
        • Shields N.
        • Brusco N.K.
        • Watts J.J.
        • Taylor N.F.
        Additional Saturday rehabilitation improves functional independence and quality of life and reduces length of stay: a randomized controlled trial.
        BMC Med. 2013; 11: 198
        • English C.
        • Bernhardt J.
        • Crotty M.
        • Esterman A.
        • Segal L.
        • Hillier S.
        Circuit class therapy or seven-day week therapy for increasing rehabilitation intensity of therapy after stroke (CIRCIT): a randomized controlled trial.
        Int J Stroke. 2015; 10: 594-602
        • Kinoshita S.
        • Kakuda W.
        • Momosaki R.
        • Yamada N.
        • Watanabe S.
        • Abo M.
        Clinical management provided by board-certificated physiatrists in early rehabilitation is a significant determinant of functional improvement in acute stroke patients: a retrospective analysis of Japan Rehabilitation Database.
        J Stroke Cerebrovasc Dis. 2015; 24: 1019-1024
        • Banks J.L.
        • Marotta C.A.
        Outcomes validity and reliability of the modified Rankin scale: implications for stroke clinical trials: a literature review and synthesis.
        Stroke. 2007; 38: 1091-1096
        • Westerkam W.R.
        • Cifu D.X.
        • Keyser L.
        Functional outcome after inpatient rehabilitation following aneurysmal subarachnoid hemorrhage: a prospective analysis.
        Top Stroke Rehabil. 1997; 4: 29-37
        • Muramatsu N.
        • Liang J.
        Hospital length of stay in the United States and Japan: a case study of myocardial infarction patients.
        Int J Health Serv. 1999; 29: 189-209
        • Denti L.
        • Agosti M.
        • Franceschini M.
        Outcome predictors of rehabilitation for first stroke in the elderly.
        Eur J Phys Rehabil Med. 2008; 44: 3-11
        • Inouye M.
        • Kishi K.
        • Ikeda Y.
        • et al.
        Prediction of functional outcome after stroke rehabilitation.
        Am J Phys Med Rehabil. 2000; 79: 513-518
        • Ween J.E.
        • Alexander M.P.
        • D'Esposito M.
        • Roberts M.
        Factors predictive of stroke outcome in a rehabilitation setting.
        Neurology. 1996; 47: 388-392
        • Di Carlo A.
        • Lamassa M.
        • Baldereschi M.
        • et al.
        Sex differences in the clinical presentation, resource use, and 3-month outcome of acute stroke in Europe: data from a multicenter multinational hospital-based registry.
        Stroke. 2003; 34: 1114-1119
        • Adams Jr., H.P.
        • Davis P.H.
        • Leira E.C.
        • et al.
        Baseline NIH Stroke Scale score strongly predicts outcome after stroke: a report of the Trial of Org 10172 in Acute Stroke Treatment (TOAST).
        Neurology. 1999; 53: 126-131
        • Seaman S.
        • Pavlou M.
        • Copas A.
        Review of methods for handling confounding by cluster and informative cluster size in clustered data.
        Stat Med. 2014; 33: 5371-5387
        • Pan W.
        Akaike's information criterion in generalized estimating equations.
        Biometrics. 2001; 57: 120-125
        • Faul F.
        • Erdfelder E.
        • Lang A.
        • Buchner A.
        G*Power 3: a flexible statistical power analysis program for the social, behavioral, and biomedical sciences.
        Behav Res Methods. 2007; 39: 175-191
        • von Elm E.
        • Altman D.G.
        • Egger M.
        • Pocock S.J.
        • Gøtzsche P.C.
        • Vandenbroucke J.P.
        • STROBE Initiative
        Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement: guidelines for reporting observational studies.
        BMJ. 2007; 335: 806-808
        • Bernhardt J.
        • Langhorne P.
        • et al.
        • AVERT Trial Collaboration group
        Efficacy and safety of very early mobilisation within 24 h of stroke onset (AVERT): a randomised controlled trial.
        Lancet. 2015; 386: 46-55
        • Bell J.A.
        • Wolke M.L.
        • Ortez R.C.
        • Jones T.A.
        • Kerr A.L.
        Training intensity affects motor rehabilitation efficacy following unilateral ischemic insult of the sensorimotor cortex in C57BL/6 mice.
        Neurorehabil Neural Repair. 2015; 29: 590-598
        • Bernhardt J.
        • Churilov L.
        • Ellery F.
        • et al.
        Prespecified dose-response analysis for A Very Early Rehabilitation Trial (AVERT).
        Neurology. 2016; 86: 2138-2145
        • Askim T.
        • Bernhardt J.
        • Salvesen O.
        • Indredavik B.
        Physical activity early after stroke and its association to functional outcome 3 months later.
        J Stroke Cerebrovasc Dis. 2014; 23: 305-312
        • Bray B.D.
        • Ayis S.
        • Campbell J.
        • et al.
        Associations between stroke mortality and weekend working by stroke specialist physicians and registered nurses: prospective multicentre cohort study.
        PLoS Med. 2014; 11: e1001705