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Current Evidence Does Not Support Exercise Therapy for Perceived Fatigue in Multiple Sclerosis

      Recently, Khan and Amatya

      Khan F, Amatya B. Rehabilitation in multiple sclerosis: a systematic review of systematic reviews. Arch Phys Med Rehabil 2016 May 20 [Epub ahead of print].

      conducted a comprehensive systematic review of systematic reviews to summarize the evidence for the effectiveness of rehabilitation interventions to improve function and participation in people with multiple sclerosis (MS). In general, they have managed to do so in a neat and concise way. However, their conclusion about the effectiveness of exercise therapy for fatigue needs reconsideration.
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      References

      1. Khan F, Amatya B. Rehabilitation in multiple sclerosis: a systematic review of systematic reviews. Arch Phys Med Rehabil 2016 May 20 [Epub ahead of print].

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      Linked Article

      • Rehabilitation in Multiple Sclerosis: A Systematic Review of Systematic Reviews
        Archives of Physical Medicine and RehabilitationVol. 98Issue 2
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          To systematically evaluate existing evidence from published systematic reviews of clinical trials for the effectiveness of rehabilitation for improving function and participation in persons with multiple sclerosis (MS).
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      • The Authors Respond
        Archives of Physical Medicine and RehabilitationVol. 97Issue 11
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          We thank Heine and deGroot for their interest in our article and comments. We agree with most comments made on the quality of evidence in individual studies included in the 3 systematic reviews for/on exercise therapy for multiple sclerosis (MS)–related fatigue. However, the evidence provided in our systematic review of systematic reviews is based on data from 3 available systematic reviews1-3 identified by the search strategy (including one conducted by Heine et al3). The findings presented were for “comprehensive fatigue management programs” for patient-reported fatigue (see below).
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