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Longitudinal Association Between Gross Motor Capacity and Neuromusculoskeletal Function in Children and Youth With Cerebral Palsy

Published:April 13, 2016DOI:https://doi.org/10.1016/j.apmr.2016.03.012

      Highlights

      • Impaired selective motor control is the strongest predictor of gross motor capacity over a large age range in children and youth with cerebral palsy.
      • Low muscle strength is predictive of a less favorable course of gross motor capacity in youth, but not in children.
      • Spasticity and reduction in range of motion of the lower extremities are less determinative of the course of gross motor capacity.

      Abstract

      Objective

      To examine associations over longitudinal measurements between neuromusculoskeletal function and gross motor capacity in children and youth with cerebral palsy (CP).

      Design

      A prospective cohort study.

      Setting

      Rehabilitation departments of university medical centers and rehabilitations centers.

      Participants

      A sample (N=327) consisting of 148 children (aged 5–9y) and 179 youth (aged 11–20y) with CP, Gross Motor Function Classification System level I (n=180), level II (n=44), level III (n=36), level IV (n=34), and level V (n=33).

      Interventions

      Not applicable.

      Main Outcome Measures

      Gross motor capacity was assessed with the Gross Motor Function Measure-66 over a period of 2 to 4 years in different age cohorts. Neuromusculoskeletal function included selective motor control (SMC), muscle strength, spasticity, and range of motion (ROM) of the lower extremities.

      Results

      Multilevel analyses showed that SMC was significantly associated with gross motor capacity in children and youth with CP, showing higher values and a more favorable course of gross motor capacity in those with better SMC. Strength was only associated with gross motor capacity in youth. Reduced ROM of hip (children) and knee extension (youth) and spasticity of the hip adductors (youth) were additionally—but more weakly—associated with lower values and a less favorable course of gross motor capacity.

      Conclusions

      Results indicate that children and youth with more severely impaired SMC and youth with reduced muscle strength have a less favorable course of gross motor capacity, while spasticity and reduced ROM are less determinative.

      Keywords

      List of abbreviations:

      CP (cerebral palsy), GMFCS (Gross Motor Function Classification System), GMFM-66 (Gross Motor Function Measure-66), PERRIN (PEdiatric Rehabilitation Research In the Netherlands), ROM (range of motion), SAROMM (Spinal Alignment and Range of Motion Measure), SMC (selective motor control)
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