Abstract
Objective
To examine the effect of participating in a 12-week supervised exercise training (ET)
program on physical activity and body composition in patients with idiopathic pulmonary
fibrosis (IPF).
Design
Randomized controlled trial assessing physical activity and body composition at baseline,
after 12-week intervention, and at 11 months follow-up.
Setting
Outpatient hospital.
Participants
Patients with IPF (N=34; mean age, 68±8y) recruited for this study; 32 patients completed
the 12-week intervention (ET group: n=15; control group: n=17) and 28 patients (14
in each group) reassessed at 11-month follow-up from baseline.
Interventions
Participation in a 12-week supervised ET program or regular medical treatment.
Main Outcome Measures
Changes in physical activity levels as measured by the International Physical Activity
Questionnaire.
Results
After the 12-week intervention, physical activity levels were significantly increased
in the ET group whereas the control group showed a trend toward deterioration (median
difference between the groups, 2164MET-min/wk [interquartile range, 1576MET-min/wk];
MET = metabolic equivalent; P<.001). Body composition was also significantly improved in the ET group, whereas
the control group showed an opposite trend. At 11-month follow-up, no significant
differences were observed between the 2 groups in all variables. The ET group lost
most of the achieved improvements in the outcomes and returned to near baseline levels,
whereas the control group showed a trend toward worsened outcomes.
Conclusions
Physical activity and body composition in patients with IPF were improved after a
12-week supervised ET program, although the benefits were not sustained at 11-month
follow-up. These results may support the efficacy of participation in supervised ET
to improve physical activity and body composition in patients with IPF; however, maintenance
strategies are warranted to preserve the improved outcomes.
Keywords
List of abbreviations:
6MWD (6-minute walking distance), ANOVA (analysis of variance), ET (exercise training), IPAQ (International Physical Activity Questionnaire), IPF (idiopathic pulmonary fibrosis), MET (metabolic equivalent)To read this article in full you will need to make a payment
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Article info
Publication history
Published online: February 08, 2016
Footnotes
Clinical Trial Registration No.: NCT01499745.
Disclosures: none.
Identification
Copyright
© 2016 The American Congress of Rehabilitation Medicine.
