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Sex-Specific Predictors of Inpatient Rehabilitation Outcomes After Traumatic Brain Injury

Published:January 30, 2016DOI:https://doi.org/10.1016/j.apmr.2016.01.011

      Abstract

      Objective

      To identify sex-specific predictors of inpatient rehabilitation outcomes among patients with a traumatic brain injury (TBI) from a population-based perspective.

      Design

      Retrospective cohort study.

      Setting

      Inpatient rehabilitation.

      Participants

      Patients in inpatient rehabilitation for a TBI within 1 year of acute care discharge between 2008/2009 and 2011/2012 (N=1730, 70% men, 30% women).

      Interventions

      None.

      Main Outcome Measures

      Inpatient rehabilitation length of stay, total FIM score, and motor and cognitive FIM ratings at discharge.

      Results

      Sex, as a covariate in multivariable linear regression models, was not a significant predictor of rehabilitation outcomes. Although many of the predictors examined were similar across men and women, sex-specific multivariable models identified some predictors of rehabilitation outcome that are specific for men and women; mechanism of injury (P<.0001) was a significant predictor of functional outcome only among women, whereas comorbidities (P<.0001) was a significant predictor for men only.

      Conclusions

      Predictors of outcomes after inpatient rehabilitation differed by sex, providing evidence for a sex-specific approach in planning and resource allocation for inpatient rehabilitation services for patients with TBI.

      Keywords

      List of abbreviations:

      ADG (Aggregated Diagnosis Group), AIS (Abbreviated Injury Score), ALC (alternate level of care), DAD (Discharge Abstract Database), LOS (length of stay), MVC (motor vehicle collision), NRS (National Rehabilitation Reporting System), TBI (traumatic brain injury)
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