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Effects of a Novel Therapeutic Intervention in Patients With Diabetic Peripheral Neuropathy

Published:January 22, 2016DOI:https://doi.org/10.1016/j.apmr.2015.12.026

      Abstract

      Objective

      To determine the effect of a novel therapeutic intervention called intraneural facilitation on balance measures and a neuropathy scale in patients with diabetic peripheral neuropathy.

      Design

      Prospective pre- and posttest, single group clinical trial.

      Setting

      Outpatient physical therapy clinic.

      Participants

      Patients with diabetic peripheral neuropathy (N=13).

      Intervention

      Subjects received 10 sessions of intraneural facilitation.

      Main Outcome Measures

      The modified Total Neuropathy Scale, the NeuroCom SMART Balance Master system computerized dynamic posturography (CDP) that includes the Sensory Organization Test (SOT) and the limits of stability (LOS), and the Activities-specific Balance and Confidence (ABC) scale.

      Results

      Subjects in this study showed significant improvement in the modified Total Neuropathy Scale, SOT, and 1 component in the LOS test (movement velocity). There were no significant differences in the ABC scale or in 4 components of the LOS test, which were reaction time, end point excursion, maximum excursion, and directional control.

      Conclusions

      Intraneural facilitation improved objective balance measures and neuropathy symptoms in patients with diabetic peripheral neuropathy. Further study is needed to determine long-term benefits of this intervention.

      Keywords

      List of abbreviations:

      ABC (Activities-specific Balance Confidence), CDP (computerized dynamic posturography), DM (diabetes mellitus), DPN (diabetic peripheral neuropathy), DSPN (distal symmetric polyneuropathy), LOS (limits of stability), SOT (Sensory Organization Test)
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