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Original research| Volume 96, ISSUE 12, P2137-2144, December 2015

Proximal Fugl-Meyer Assessment Scores Predict Clinically Important Upper Limb Improvement After 3 Stroke Rehabilitative Interventions

  • Author Footnotes
    ∗ Lee and Hsieh contributed equally to this work.
    Ya-yun Lee
    Footnotes
    ∗ Lee and Hsieh contributed equally to this work.
    Affiliations
    Department of Occupational Therapy and Graduate Institute of Behavioral Sciences, College of Medicine, Chang Gung University, Taoyuan, Taiwan

    Healthy Aging Research Center, Chang Gung University, Taoyuan, Taiwan
    Search for articles by this author
  • Author Footnotes
    ∗ Lee and Hsieh contributed equally to this work.
    Yu-wei Hsieh
    Footnotes
    ∗ Lee and Hsieh contributed equally to this work.
    Affiliations
    Department of Occupational Therapy and Graduate Institute of Behavioral Sciences, College of Medicine, Chang Gung University, Taoyuan, Taiwan

    Healthy Aging Research Center, Chang Gung University, Taoyuan, Taiwan
    Search for articles by this author
  • Ching-yi Wu
    Affiliations
    Department of Occupational Therapy and Graduate Institute of Behavioral Sciences, College of Medicine, Chang Gung University, Taoyuan, Taiwan

    Healthy Aging Research Center, Chang Gung University, Taoyuan, Taiwan
    Search for articles by this author
  • Keh-chung Lin
    Correspondence
    Corresponding author Keh-chung Lin, ScD, OTR, School of Occupational Therapy, College of Medicine, National Taiwan University, 17, F4, Xu Zhou Rd, Taipei 100, Taiwan.
    Affiliations
    School of Occupational Therapy, College of Medicine, National Taiwan University, Taipei, Taiwan
    Search for articles by this author
  • Chih-kuang Chen
    Affiliations
    Department of Physical Medicine and Rehabilitation, Chang Gung Memorial Hospital at Taoyuan, Taoyuan, Taiwan

    School of Medicine, Chang Gung University, Taoyuan, Taiwan
    Search for articles by this author
  • Author Footnotes
    ∗ Lee and Hsieh contributed equally to this work.
Published:August 07, 2015DOI:https://doi.org/10.1016/j.apmr.2015.07.019

      Abstract

      Objective

      To identify the baseline motor characteristics of the patients who responded to 3 prominent intervention programs.

      Design

      Observational cohort study.

      Setting

      Outpatient rehabilitation clinics.

      Participants

      Individuals with chronic stroke (N=174).

      Interventions

      Participants received 30 hours of constraint-induced movement therapy (CIMT), robot-assisted therapy, or mirror therapy (MT).

      Main Outcome Measures

      The primary outcome measure was the change score of the Upper Extremity Fugl-Meyer Assessment (UE-FMA). The potential predicting variables were baseline proximal, distal, and total UE-FMA and Action Research Arm Test scores. We combined polynomial regression analyses and the minimal clinically important difference to stratify the patients as responders and nonresponders for each intervention approach.

      Results

      Baseline proximal UE-FMA scores significantly predicted clinically important improvement on the primary outcome measure after all 3 interventions. Participants with baseline proximal UE-FMA scores of approximately <30 benefited significantly from CIMT and robot-assisted therapy, whereas participants with scores between 21 and 35 demonstrated significant improvement after MT. Baseline distal and total UE-FMA and Action Research Arm Test scores could also predict upper limb improvement after CIMT and MT, but not after robot-assisted therapy.

      Conclusions

      This study could inform clinicians about the selection of suitable rehabilitation approaches to help patients achieve clinically meaningful improvement in upper extremity function.

      Keywords

      List of abbreviations:

      ARAT (Action Research Arm Test), CIMT (constraint-induced movement therapy), FMA (Fugl-Meyer Assessment), MCID (minimal clinically important difference), MG (mesh glove), MT (mirror therapy), UE (upper extremity), UE-FMA (Upper Extremity Fugl-Meyer Assessment)
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