Abstract
Objective
To compare the mortality rate and the rate of subsequent ischemic events (myocardial
infarction [MI], ischemic stroke, or limb amputation) in patients with recent MI according
to the use of cardiac rehabilitation or no rehabilitation.
Design
Longitudinal observational study.
Setting
Ongoing registry of outpatients.
Participants
Patients (N=1043) with recent acute MI were recruited; of these, 521 (50%) participated
in cardiac rehabilitation.
Interventions
Not applicable.
Main Outcome Measures
Subsequent ischemic events and mortality rates were registered.
Results
Over a mean follow-up of 18 months, 50 patients (4.8%) died and 49 (4.7%) developed
52 subsequent ischemic events (MI: n=43, ischemic stroke: n=6, limb amputation: n=3).
Both the mortality rate (.16 vs 5.57 deaths per 100 patient-years; rate ratio=.03;
95% confidence interval [CI], 0.0–0.1]) and the rate of subsequent ischemic events
(1.65 vs 4.54 events per 100 patient-years; rate ratio=0.4; 95% CI, 0.2–0.7) were
significantly lower in cardiac rehabilitation participants than in nonparticipants.
Multivariate analysis confirmed that patients in cardiac rehabilitation had a significantly
lower risk of death (hazard ratio=.08; 95% CI, .01–.63; P=.016) and a nonsignificant lower risk of subsequent ischemic events (hazard ratio=.65;
95% CI, .30–1.42).
Conclusions
The use of cardiac rehabilitation in patients with recent MI was independently associated
with a significant decrease in the mortality rate and a nonsignificant decrease in
the rate of subsequent ischemic events.
List of abbreviations:
CI (confidence interval), FRENA (Risk Factors and Arterial Disease), MI (myocardial infarction)To read this article in full you will need to make a payment
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Article info
Publication history
Published online: October 11, 2013
Footnotes
No commercial party having a direct financial interest in the results of the research supporting this article has or will confer a benefit on the authors or on any organization with which the authors are associated.
Identification
Copyright
© 2014 American Congress of Rehabilitation Medicine. Published by Elsevier Inc. All rights reserved.
