Abstract
Objectives
To identify randomized controlled trials comparing the use of hydrophilic and nonhydrophilic
catheters for intermittent catheterization (IC) in patients with spinal cord injury
(SCI), and to perform a meta-analysis evaluating the occurrence of hematuria and urinary
tract infection (UTI).
Data Sources
We searched the following electronic databases to identify studies: EMBASE (1991 to
August 2011), PubMed (1991 to August 2011), Cochrane Library (no date restriction),
China National Knowledge Infrastructure (no date restriction), and the Chinese Biomedical
Literature Database (no date restriction).
Study Selection
Randomized controlled trials, parallel-control, crossover-control, and prospective
cohort studies that assessed morbidity associated with the use of hydrophilic catheters
and nonhydrophilic catheters in patients after SCI were included.
Data Extraction
Data extraction was performed using standardized forms of the Cochrane Collaboration.
Methodologic quality was independently assessed by 2 reviewers using the Downs and
Black instrument. Pooled odds ratios (ORs) with 95% confidence intervals (CIs) were
calculated for dichotomous data.
Data Synthesis
Five studies involving 508 subjects; 462 subjects completed the study and were included
in this meta-analysis. There was a significantly lower incidence (OR=.36; 95% CI,
24%–54%; P<.0001) of reported UTIs in the hydrophilic-treated group compared with the nonhydrophilic-treated
group. Hematuria was also reported significantly less in the hydrophilic catheter
group than in the nonhydrophilic catheter group (OR=.57; 95% CI, 35%–92%; P=.001).
Conclusions
This meta-analysis found UTIs and hematuria less frequently associated with the use
of hydrophilic-coated catheters for IC in patients with SCI. These findings support
the use of hydrophilic catheters in this patient population.
Keywords
List of abbreviations:
CI (confidence interval), CIC (clean intermittent catheterization), CNKI (China National Knowledge Infrastructure), EMBASE (Excerpta Medica Database), IC (intermittent catheterization), MeSH (Medical Subject Heading), OR (odds ratio), SCI (spinal cord injury), UTI (urinary tract infection)To read this article in full you will need to make a payment
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Article info
Publication history
Published online: November 19, 2012
Footnotes
Supported by the Shanghai Science and Technical Committee Foundation of China (grant no. 044119610).
No commercial party having a direct financial interest in the results of the research supporting this article has or will confer a benefit on the authors or on any organization with which the authors are associated.
Identification
Copyright
© 2013 American Congress of Rehabilitation Medicine. Published by Elsevier Inc. All rights reserved.
