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Active-Assisted Cycling Improves Tremor and Bradykinesia in Parkinson's Disease

      Abstract

      Ridgel AL, Peacock CA, Fickes EJ, Kim C-H. Active-assisted cycling improves tremor and bradykinesia in Parkinson's disease.

      Objectives

      To develop a rapid cadence cycling intervention (active-assisted cycling [AAC]) using a motorized bike and to examine physiological perimeters during these sessions in individuals with Parkinson's disease (PD). A secondary goal was to examine whether a single session of AAC at a high cadence would promote improvements in tremor and bradykinesia similar to the on medication state.

      Design

      Before-after pilot trial with cross-over.

      Setting

      University research laboratory.

      Participants

      Individuals with idiopathic PD (N=10, age 45–74y) in Hoehn and Yahr stages 1 to 3.

      Intervention

      Forty minutes of AAC.

      Main Outcome Measures

      Heart rate, pedaling power, and rating of perceived exertion were recorded before, during, and after a bout of AAC. Functional assessments included tremor score during resting, postural, and kinetic tremor.

      Results

      This AAC paradigm was well tolerated by individuals with PD without excessive fatigue, and most participants showed improvements in tremor and bradykinesia immediately after a single bout of cycling.

      Conclusions

      This paradigm could be used to examine changes in motor function in individuals with PD after bouts of high-intensity exercise.

      Key Words

      List of Abbreviations:

      AAC (active-assisted cycling), BWSTT (body weight–supported treadmill training), CI (confidence interval), PD (Parkinson's disease), RPE (rating of perceived exertion), rpm (revolutions per minute), UPDRS (Unified Parkinson's Disease Rating Scale), V̇o2max (maximum oxygen consumption)
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