Brief report| Volume 93, ISSUE 10, P1868-1871, October 2012

Long-Term Outcomes in Fibromyalgia Patients Treated With Noninvasive Cortical Electrostimulation

Published:April 23, 2012DOI:


      Hargrove JB, Bennett RM, Clauw DJ. Long-term outcomes in fibromyalgia patients treated with noninvasive cortical electrostimulation.


      To evaluate long-term outcomes of a noninvasive cortical stimulation technology in the treatment of fibromyalgia (FM).


      After trial follow-up survey of subjects who had completed a randomized, controlled, double-blind study of noninvasive cortical stimulation therapy some 45 months previously.


      General community.


      Patients with FM (N=69) who participated in the previous study, 39 of whom were mailed surveys.


      Not applicable.

      Main Outcome Measure

      Changes in the Fibromyalgia Impact Questionnaire.


      There was a 64% survey return rate. The total Fibromyalgia Impact Questionnaire score was 52.6 at baseline, 35.7 at end of study, and 31.8 at follow-up (P<.001). Subjects reported symptom improvements lasting at least 2 years, with a reduction or elimination of medicine use and need to see physicians for FM.


      A high percentage of patients with FM treated with noninvasive cortical stimulation continued to experience worthwhile improvement at follow-up.

      Key Words

      List of Abbreviations:

      BOCF (baseline observation carried forward), EOS (end of study), FIQ (Fibromyalgia Impact Questionnaire), FM (fibromyalgia), RINCE (reduced impedance noninvasive cortical electrostimulation)
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