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Resistance Training Dose Response in Combined Endurance-Resistance Training in Patients With Cardiovascular Disease: A Randomized Trial

Published:August 29, 2011DOI:https://doi.org/10.1016/j.apmr.2011.04.021

      Abstract

      Berent R, von Duvillard SP, Crouse SF, Sinzinger H, Green JS, Schmid P. Resistance training dose response in combined endurance-resistance training in patients with cardiovascular disease: a randomized trial.

      Objective

      To compare the effectiveness of 2 different volumes of resistance training (RT) combined with aerobic training in residential cardiac rehabilitation (CR).

      Design

      Randomized prospective cohort study.

      Setting

      Center for inpatient CR.

      Participants

      Patients (N=295) with a mean age ± SD of 62.7±11.7 years participated in the study.

      Interventions

      Patients were randomly divided into 2 groups (group 1 and group 2) with different volumes of RT; 2 sets × 12 repetitions (REPS) (group 1) and 3 sets × 15 REPS (group 2) per session, 2 times per week; each RT session consisting of 10 different resistance exercises. In addition, patients also completed continuous moderate intensity aerobic training composed of cycle ergometry 6 times per week for 17±4 minutes (mean ± SD) and walking 5 times per week for 45 minutes.

      Main Outcome Measures

      At entry and after 26±4 (mean ± SD) days of CR, blood pressure, heart rate, maximal oxygen consumption, and maximal power determined during cycle ergometry, strength determined via RT, and blood biochemistries were assessed. Data were analyzed via a 2-way (group × time) repeated measures analysis of variance.

      Results

      Statistical analysis revealed equivalent improvements in exercise capacity, muscular strength, hemodynamics, and blood chemistries regardless of RT volume (comparison-wise type I error rate, α<.01).

      Conclusions

      Our results show that nearly doubling (3 sets × 15 REPS vs 2 sets × 12 REPS) the volume of RT as part of a residential CR program does not yield further improvement in strength and cardiovascular risk factors.

      Key Words

      Abbreviations:

      ANOVA (analysis of variance), CR (cardiac rehabilitation), CVD (cardiovascular disease), EF (ejection fraction), 1RM (1-repetition maximum), RPE (ratings of perceived exertion), REPS (repetitions), RT (resistance training), V̇o2max (maximal oxygen uptake), Wmax (maximal performance)
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