Advertisement

The Authors Respond

  • Mira Meeus
    Affiliations
    Department of Human Physiology, Faculty of Physical Education & Physiotherapy, Vrije Universiteit Brussel, Brussels, Belgium, Division of Musculoskeletal Physiotherapy, Department of Health Care Sciences, Artesis University College, Antwerp, Belgium
    Search for articles by this author
  • Jo Nijs
    Affiliations
    Department of Human Physiology, Faculty of Physical Education and Physiotherapy, Vrije Universiteit Brussel, Brussels, Belgium, Division of Musculoskeletal Physiotherapy, Department of Health Care Sciences, Artesis University College, Antwerp, Belgium, Department of Physical Medicine and Physiotherapy, University Hospital Brussels, Brussels, Belgium
    Search for articles by this author
  • Jessica Van Oosterwijck
    Affiliations
    Department of Human Physiology, Faculty of Physical Education and Physiotherapy, Vrije Universiteit Brussel, Brussels, Belgium, Division of Musculoskeletal Physiotherapy, Department of Health Care Sciences, Artesis University College, Antwerp, Belgium, Department of Physical Medicine and Physiotherapy, University Hospital Brussels, Brussels, Belgium
    Search for articles by this author
  • Kelly Ickmans
    Affiliations
    Department of Human Physiology, Faculty of Physical Education and Physiotherapy, Vrije Universiteit Brussel, Brussels, Belgium, Division of Musculoskeletal Physiotherapy, Department of Health Care Sciences, Artesis University College, Antwerp, Belgium, Department of Physical Medicine and Physiotherapy, University Hospital Brussels, Brussels, Belgium
    Search for articles by this author
      We are pleased with the discussion
      • Kindlon T.
      Educational programs for chronic fatigue syndrome need to take cognizance of the condition's abnormal response to exercise.
      after the publication of our randomized controlled trial examining the effectiveness of pain physiology education in people with chronic fatigue syndrome (CFS).
      • Meeus M.
      • Nijs J.
      • Van Oosterwijck J.
      • Van Alsenoy V.
      • Truijen S.
      Pain physiology education improves pain beliefs in patients with chronic fatigue syndrome compared with pacing and self-management education: a double-blind randomized controlled trial.
      As we reported ourselves, too vigorous exercise can indeed be harmful for patients with CFS.

      Meeus M, Roussel NA, Truijen S, Nijs J. Reduced pressure pain thresholds in response to exercise in chronic fatigue syndrome but not in chronic low back pain: an experimental study. J Rehabil Med;42:884-90.

      • Nijs J.
      • Van Oosterwijck J.
      • Meeus M.
      • et al.
      Unravelling the nature of postexertional malaise in myalgic encephalomyelitis/chronic fatigue syndrome: the role of elastase, complement C4a and interleukin-1beta.
      • Van Oosterwijck J.
      • Nijs J.
      • Meeus M.
      • et al.
      Pain inhibition and postexertional malaise in myalgic encephalomyelitis/chronic fatigue syndrome: an experimental study.
      Submaximal and even self-paced limited exercise causes a decrease in pain thresholds,

      Meeus M, Roussel NA, Truijen S, Nijs J. Reduced pressure pain thresholds in response to exercise in chronic fatigue syndrome but not in chronic low back pain: an experimental study. J Rehabil Med;42:884-90.

      • Van Oosterwijck J.
      • Nijs J.
      • Meeus M.
      • et al.
      Pain inhibition and postexertional malaise in myalgic encephalomyelitis/chronic fatigue syndrome: an experimental study.
      increased symptom intensity,
      • Van Oosterwijck J.
      • Nijs J.
      • Meeus M.
      • et al.
      Pain inhibition and postexertional malaise in myalgic encephalomyelitis/chronic fatigue syndrome: an experimental study.
      further immune dysregulation,
      • Sorensen B.
      • Streib J.E.
      • Strand M.
      • et al.
      Complement activation in a model of chronic fatigue syndrome.
      and increased oxidative stress.
      • Jammes Y.
      • Steinberg J.G.
      • Mambrini O.
      • Bregeon F.
      • Delliaux S.
      Chronic fatigue syndrome: assessment of increased oxidative stress and altered muscle excitability in response to incremental exercise.
      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'

      Subscribe:

      Subscribe to Archives of Physical Medicine and Rehabilitation
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect

      References

        • Kindlon T.
        Educational programs for chronic fatigue syndrome need to take cognizance of the condition's abnormal response to exercise.
        Arch Phys Med Rehabil. 2011; 92 (xxx)
        • Meeus M.
        • Nijs J.
        • Van Oosterwijck J.
        • Van Alsenoy V.
        • Truijen S.
        Pain physiology education improves pain beliefs in patients with chronic fatigue syndrome compared with pacing and self-management education: a double-blind randomized controlled trial.
        Arch Phys Med Rehabil. 2010; 91: 1153-1159
      1. Meeus M, Roussel NA, Truijen S, Nijs J. Reduced pressure pain thresholds in response to exercise in chronic fatigue syndrome but not in chronic low back pain: an experimental study. J Rehabil Med;42:884-90.

        • Nijs J.
        • Van Oosterwijck J.
        • Meeus M.
        • et al.
        Unravelling the nature of postexertional malaise in myalgic encephalomyelitis/chronic fatigue syndrome: the role of elastase, complement C4a and interleukin-1beta.
        J Intern Med. 2010; 267: 418-435
        • Van Oosterwijck J.
        • Nijs J.
        • Meeus M.
        • et al.
        Pain inhibition and postexertional malaise in myalgic encephalomyelitis/chronic fatigue syndrome: an experimental study.
        J Intern Med. 2010; 268: 265-278
        • Sorensen B.
        • Streib J.E.
        • Strand M.
        • et al.
        Complement activation in a model of chronic fatigue syndrome.
        J Allergy Clin Immunol. 2003; 112: 397-403
        • Jammes Y.
        • Steinberg J.G.
        • Mambrini O.
        • Bregeon F.
        • Delliaux S.
        Chronic fatigue syndrome: assessment of increased oxidative stress and altered muscle excitability in response to incremental exercise.
        J Intern Med. 2005; 257: 299-310
        • Meeus M.
        • Nijs J.
        • Van de Wauwer N.
        • Toeback L.
        • Trujen S.
        Diffuse noxious inhibitory control is delayed in chronic fatigue syndrome: an experimental study.
        Pain. 2008; 139: 439-448
        • Brosschot J.F.
        Cognitive-emotional sensitization and somatic health complaints.
        Scand J Psychol. 2002; 43: 113-121
        • Van Oosterwijck J.
        • Nijs J.
        • Meeus M.
        • et al.
        Pain neurophysiology education improves cognitions, pain thresholds and movement performance in people with chronic whiplash: a pilot study.
        J Rehabil Res Dev. 2011; 48: 43-58
        • Ang D.C.
        • Chakr R.
        • Mazzuca S.
        • France C.R.
        • Steiner J.
        • Stump T.
        Cognitive-behavioral therapy attenuates nociceptive responding in patients with fibromyalgia: a pilot study.
        Arthritis Care Res. 2010; 62: 618-623

      Linked Article

      • Educational Programs for Chronic Fatigue Syndrome Need to Take Cognizance of the Condition's Abnormal Response to Exercise
        Archives of Physical Medicine and RehabilitationVol. 92Issue 6
        • Preview
          I read the article by Meeus et al1 with interest, but question some of its logic. A “healthy eating” education program could be of benefit to most in society; however, unless it was specifically tailored for people with unusual reactions to some foods, for example people with coeliac disease, it might not be beneficial and could actually harm such individuals. Similarly, given the abnormal response of people with chronic fatigue syndrome (CFS) to exercise,2-5 one cannot simply assume a pain management program that is suitable for other groups, such as those with chronic lower back pain (CLBP), will be appropriate and safe in CFS.
        • Full-Text
        • PDF