Abstract
Castiglione A, Bagnato S, Boccagni C, Romano MC, Galardi G. Efficacy of intra-articular
injection of botulinum toxin type A in refractory hemiplegic shoulder pain.
Objective
To evaluate the efficacy of intra-articular injection of botulinum toxin type A (BTX-A)
in relieving hemiplegic shoulder pain (HSP).
Design
Pilot study with assessments before and after BTX-A intra-articular injection.
Setting
Hospital rehabilitation department.
Participants
Patients (N=5) with HSP refractory to standard treatments and pain score at rest greater
than 7 on a pain visual analog scale (VAS) of 0 to 10cm.
Intervention
Intra-articular BTX-A injection.
Main Outcome Measure
Variation in VAS score at rest and during 90° passive arm abduction 2 and 8 weeks
after BTX-A intra-articular injection.
Results
Baseline VAS score was 8.7±1 at rest and 9.8±0.4 during passive arm abduction. It
clearly decreased at 2 (1.5±1.1 at rest, P=.001; 3±1.2 during arm abduction, P<.001) and 8 weeks (1.5±1.2 at rest, P=.001; 2.3±1.1 during arm abduction, P<.001) after BTX-A intra-articular injection.
Conclusions
We found a strong correlation between intra-articular BTX-A injection and pain relief
in patients with HSP. This result could provide the rationale for blind randomized
controlled trials designed to better evaluate the safety and efficacy of intra-articular
BTX-A injection in patients with refractory HSP.
Key Words
List of Abbreviations:
BTX-A (botulinum toxin type A), HSP (hemiplegic shoulder pain), VAS (visual analog scale)To read this article in full you will need to make a payment
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Article info
Footnotes
No commercial party having a direct financial interest in the results of the research supporting this article has or will confer a benefit on the authors or on any organization with which the authors are associated.
Identification
Copyright
© 2011 American Congress of Rehabilitation Medicine. Published by Elsevier Inc. All rights reserved.
