Treger I, Aidinof L, Lutsky L, Kalichman L. Mean flow velocity in the middle cerebral artery is associated with rehabilitation success in ischemic stroke patients.
To evaluate the association between mean flow velocity (MFV) in the middle cerebral artery (MCA) measured by using transcranial Doppler (TCD) and functional and neurologic impairment change during rehabilitation after acute stroke.
Cross-sectional observational study.
Acute neurologic rehabilitation department.
Consecutive patients (N=67; 53 men, 14 women; mean ± SD age, 61.54±8.92y) referred to the rehabilitation center during the first 6 months of 2006 for a first ischemic stroke in the MCA area.
Main Outcome Measures
All subjects were evaluated on admission and at discharge by using the National Institutes of Health Stroke Scale (NIHSS) and the FIM. TCD measurements of MFV of the ipsilateral and contralateral MCA were performed on admission (during the first 20 days after stroke) and a few days before discharge.
Contralateral MFV at admission was associated significantly with all indexes of functional rehabilitation success (FIM score at discharge [β=.169; P=.010], change in FIM score [β=.554; P=.010], relative improvement in FIM score [β=.783; P=.003]). No significant association was found between indexes of NIHSS change and ipsilateral or contralateral MFV.
Ipsilateral or contralateral MFV measured at admission did not change during the 2-month rehabilitation period. Our data showed a significant association between blood flow velocity in the contralateral MCA and functional rehabilitation parameters of patients after first ischemic stroke in the MCA area.
List of Abbreviations:ΔFIM (change in FIM score), ΔNIHSS (change in NIHSS score), MCA (middle cerebral artery), MFV (mean flow velocity), NIHSS (National Institutes of Health Stroke Scale), RI-FIM (relative improvement in FIM score), TCD (transcranial Doppler)
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- The Stroke Data Bank: design, methods, and baseline characteristics.Stroke. 1988; 19: 547-554
- Prognostic use of ultrasonography in acute non-hemorrhagic carotid stroke.Ital J Neurol Sci. 1996; 17: 215-218
- Haemodynamic studies in early stroke.J Neurol. 1992; 239: 138-142
- Intracranial blood flow velocities in acute ischemic stroke.Stroke. 1994; 25: 1378-1383
- Progression and clinical recurrence of symptomatic middle cerebral artery stenosis: a long-term follow-up transcranial Doppler ultrasound study.Stroke. 2001; 32: 2898-2904
- The relationship between mean flow velocity and functional and neurologic parameters of ischemic stroke patients undergoing rehabilitation.Arch Phys Med Rehabil. 2005; 86: 427-430
- Functional measures of first-stroke rehabilitation inpatients: usefulness of the Functional Independence Measure total score with a clinical rationale.Arch Phys Med Rehabil. 1997; 78: 630-635
- Anatomy and freehand examination techniques.in: Newell D.W. Aaslid R. Transcranial Doppler. Raven Pr, New York1992: 9-31
- Transcranial Doppler ultrasonography.Mosby-Year Book, St Louis1993
- Noninvasive transcranial Doppler ultrasound recording of flow velocity in basal cerebral arteries.J Neurosurg. 1982; 57: 769-774
- Prediction of early neurological deterioration using diffusion- and perfusion-weighted imaging in hyperacute middle cerebral artery ischemic stroke.Stroke. 2002; 33: 2197-2203
- Comparison of cerebral angiography and transcranial Doppler sonography in acute stroke.Stroke. 1989; 20: 899-903
- Clinical and instrumental evaluation of patients with ischemic stroke within the first six hours.J Neurol Sci. 1989; 91: 311-321
- Sex differences in stroke epidemiology: a systematic review.Stroke. 2009; 40: 1082-1090
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© 2010 American Congress of Rehabilitation Medicine. Published by Elsevier Inc. All rights reserved.