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Health-Related Quality of Life in Childhood Cerebral Palsy

  • Jilda Vargus-Adams
    Correspondence
    Reprint requests to Jilda Vargus-Adams, MD, MS, Div of Pediatric Rehabilitation, Cincinnati Children’s Hospital Medical Center, 3333 Burnet Ave, MLC 4009, Cincinnati, OH 45229.
    Affiliations
    Division of Pediatric Rehabilitation, Departments of Physical Medicine and Rehabilitation and Pediatrics, University of Cincinnati College of Medicine, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH.
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      Abstract

      Vargus-Adams J. Health-related quality of life in childhood cerebral palsy.

      Objective

      To describe the health-related quality of life (HRQOL) of a cross-section of children with cerebral palsy (CP) using the Child Health Questionnaire.

      Design

      Survey of the parents or guardians of children with CP.

      Setting

      Outpatient clinics at a tertiary care children’s hospital.

      Participants

      Children (N=177; 98 boys, 79 girls; mean age ± standard deviation [SD], 8.6±4.2y) with CP were enrolled as a convenience sample. Study subjects were stratified by severity of CP using the Gross Motor Function Classification System.

      Interventions

      Not applicable.

      Main outcome measure

      HRQOL scores, as determined by the Child Health Questionnaire–Parent Form 50.

      Results

      Parents reported reduced HRQOL for their children with CP. In the physical function domain, most children scored over 3 SDs below a normative sample, and scores in parental impact domains were at least 1 SD below the normative sample. Psychosocial domains were less impaired. Most of the effects on physical and parent impact domains were greater in children with more severe CP, although they were significant in most strata of severity.

      Conclusions

      Children with CP have reduced HRQOL and the degree to which it is reduced is related to the severity of their CP.

      Key words

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