Abstract
Klefbeck B, Hamrah Nedjad J. Effect of inspiratory muscle training in patients with
multiple sclerosis. Arch Phys Med Rehabil 2003;84:994-9.
Objective:
To evaluate whether inspiratory muscle training (IMT) improves inspiratory muscle
strength, respiratory capacity, fatigue, and subjective perception of physical endurance
in patients with advanced multiple sclerosis (MS).
Design:
Randomized controlled trial.
Setting:
Outpatient clinic in Sweden.
Participants:
Fifteen severely disabled patients with MS, randomized to a training or control group.
Intervention:
Seven patients trained with a Threshold inspiratory muscle trainer, twice every other
day, with 3 sets of 10 loaded inspirations (40%–60% of patients’ maximal inspiratory
pressure [Pimax]) over a 10-week period.
Main Outcome Measures:
Spirometry, Pimax, maximal expiratory pressure (Pemax), clinical assessments, and questionnaires on the patients’ fatigue severity and
physical endurance were evaluated.
Results:
After training, the Pimax (P<.008) and Pemax (P<.02) increased in the training group. The improvement in Pimax after 10 weeks of training was higher than the improvement in the control group
(P<.01) and was maintained 1 month after the training period ended. The training affected
neither respiratory function nor the patients’ symptoms.
Conclusions:
IMT had a beneficial effect on inspiratory muscle strength in patients with MS and
is recommended as a complement to ordinary physical training.
Keywords
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References
- Multiple sclerosis.Semin Neurol. 1998; 18: 337-349
- Neuropathology in multiple sclerosis.Mult Scler. 1998; 4: 93-98
- Churchill Livingstone, London1985: 49-73 McAlpine’s multiple sclerosis. Course and prognosis.
- New diagnostic criteria for multiple sclerosis.Ann Neurol. 1983; 13: 227-231
- Clinical definition for multiple sclerosis treatment trials.Ann Neurol. 1994; 36: 73-79
- Multiple sclerosis. The problem of incorrect diagnosis.Arch Neurol. 1986; 43: 578-583
- The respiratory system in neuromuscular disorders.in: Roussos C. Macklem P.T. The thorax: lung biology in health and disease. Marcel Dekker, New York1985: 2135-2140
- Pulmonary function and dysfunction in multiple sclerosis.Arch Neurol. 1988; 45: 1245-1249
- Respiratory dysfunction in multiple sclerosis.Eur Respir J. 1997; 10: 139-145
- Control of breathing and respiratory muscle strength in patients with multiple sclerosis.Chest. 1994; 105: 1163-1170
- Cause of death in patients attending multiple sclerosis clinics.Neurology. 1991; 41: 1193-1196
- Respiratory involvement in multiple sclerosis.Brain. 1992; 115: 479-494
- Chapman & Hall, London1996: 1-163 Physiotherapy in respiratory care: a problem-solving approach to respiratory and cardiac management. 2nd ed.
- Respiratory muscle function and exercise capacity in multiple sclerosis.Eur Respir J. 1994; 7: 23-28
- The nature of fatigue in multiple sclerosis.J Psychosom Res. 1998; 45: 33-38
- The measurement of fatigue in patients with multiple sclerosis.Arch Neurol. 1996; 53: 642-649
- Evaluation of the THRESHOLD® trainer for inspiratory muscle endurance training.Eur Respir J. 1996; 9: 2681-2684
- Inspiratory muscle training protocol using a pressure threshold device.Arch Phys Med Rehabil. 1999; 80: 100-102
- Inspiratory muscle training in patients with bronchial asthma.Chest. 1992; 102: 1357-1361
- Inspiratory muscle training combined with general exercise reconditioning in patients with COPD.Chest. 1992; 102: 1351-1356
- Targeted inspiratory muscle training improves respiratory muscle function and reduces dyspnea in patients with chronic obstructive pulmonary diseases.Ann Intern Med. 1989; 111: 117-124
- Inspiratory muscle training in chronic airflow limitation.Eur Respir J. 1994; 7: 1266-1274
- Ventilatory responses to inspiratory threshold loading and role of muscle fatigue in task failure.J Appl Physiol. 1994; 76: 185-195
- Inspiratory muscle training in patients with prior polio who use part-time assisted ventilation.Arch Phys Med Rehabil. 2000; 81: 1065-1071
- Pressure-flow effects on endurance of inspiratory muscles.J Appl Physiol. 1986; 60: 299-303
- Rating neurologic impairment in multiple sclerosis.Neurology. 1983; 33: 1444-1452
- Maximal respiratory pressures.Am Rev Respir Dis. 1969; 99: 696-702
- Learning effects, variation during office hours and reproducibility of static and dynamic spirometry.Respiration. 1987; 51: 214-222
- How many manoeuvers should be done to measure maximal inspiratory mouth pressure in patients with chronic airflow obstruction?.Thorax. 1989; 44: 419-421
- Reliability of maximal respiratory pressures in multiple sclerosis.Chest. 1999; 115: 1546-1552
- Reliability of maximal inspiratory pressure.Nurs Res. 1987; 36: 317-319
- Predicted normal values for maximal respiratory pressures in Caucasian adults and children.Thorax. 1984; 39: 535-538
- Effect of altitude on spirometric parameters and the performance of peak flow meters.Thorax. 1996; 51: 175-178
- Long term performance of a hand held spirometer.Thorax. 1996; 51: 973-976
- Standardization of lung function tests.Bull Eur Physiopathol Respir. 1983; 19: 1-95
- Standardization of spirometry—1987 update.Am Rev Respir Dis. 1987; 136: 1285-1298
- The fatigue severity scale. Application to patients with multiple sclerosis and systemic lupus erythematosus.Arch Neurol. 1989; 46: 1121-1123
- Psychophysical bases of perceived exertion.Med Sci Sports Exerc. 1982; 14: 377-381
- Expiratory training in multiple sclerosis.Arch Phys Med Rehabil. 1996; 77: 909-912
- Respiratory muscle training in multiple sclerosis.Schweiz Arch Neurol Psychiatr. 1989; 140: 46-50
- Respiratory muscle weakness and respiratory muscle training in severely disabled multiple sclerosis patients.Arch Phys Med Rehabil. 2000; 81: 747-751
Article info
Footnotes
☆Supported by the Swedish Association of the Neurologically Disabled, Norrbacka-Eugeniastiflelsen, the Foundation of the Swedish Committee for Rehabilitation, and Handicap & Habilitation, Stockholm County Council.
Identification
Copyright
© 2003 The American Congress of Rehabilitation Medicine and the American Academy of Physical Medicine and Rehabilitation. Published by Elsevier Inc. All rights reserved.