Abstract
Park ES, Park CI, Kim DY, Kim YR. The effect of spasticity on cortical somatosensory-evoked
potentials: changes of cortical somatosensory-evoked potentials after botulinum toxin
type A injection. Arch Phys Med Rehabil 2002:83:1592-6. Objective: To evaluate the changes in cortical somatosensory-evoked potentials (SEPs) after
botulinum toxin type A injection to determine what effect spasticity has on cortical
SEPs. Design: Intervention study and before-after trial. Setting: University-affiliated hospital in Korea. Participants: Twelve children with spastic hemiplegic cerebral palsy (CP), 7 children with spastic
diplegic CP, and 8 patients with traumatic brain injury. Intervention: All participants had botulinum toxin type A injected into the muscles of the spastic
limb. Main Outcome Measures: SEPs were recorded before and 7 days after the botulinum toxin type A injection.
Spasticity of the affected spastic limb was also measured. The short latency and amplitude
of waves in SEPs were measured. The SEP results were divided into 3 groups: flat (no
evoked potential), abnormal (evoked but delayed in latency), and normal (clear waveform
with normal latency). Results: The normal response of cortical SEP increased after injection. The SEPs exhibited
more frequent improvement in the limbs, with greater improvement of spasticity in
grade (>1.0 grade) and in patients of younger age (<3y) after injection (P<.05). Conclusion: The observed improvement of cortical SEPs with associated reduction of spasticity
that occurred after the botulinum toxin type A injection indicates that spasticity
itself can be considered a factor affecting cortical SEPs. © 2002 by the American Congress of Rehabilitation Medicine and the American Academy
of Physical Medicine and Rehabilitation
Keywords
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Footnotes
☆No commercial party having a direct financial interest in the results of the research supporting this article has or will confer a benefit upon the author(s) or upon any organization with which the author(s) is/are associated.
☆☆Reprint requests to Yong Rae Kim, MD, Rehabilitation Dept, Severance Hospital, Yonsei University College of Medicine, CPO Box 8044, #120-752, Seoul, Korea, e-mail: [email protected]
★Suppliers
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© 2002 American Congress of Rehabilitation Medicine and the American Academy of Physical Medicine and Rehabilitation. Published by Elsevier Inc. All rights reserved.
