Abstract
Hsieh L-F, Hsu W-C, Lin Y-J, Chang H-L, Chen C-C, Huang V. Addition of intra-articular
hyaluronate injection to physical therapy program produces no extra benefits in patients
with adhesive capsulitis of the shoulder: a randomized controlled trial.
Objective
To compare the efficacy of intra-articular hyaluronic acid (HA) injections plus physical
therapy (PT) with that of PT alone for the treatment of adhesive capsulitis (AC) of
the shoulder.
Design
Prospective, randomized controlled trial.
Setting
Rehabilitation and orthopedics department of a private teaching hospital.
Participants
Patients (N=70) with AC of the shoulder were randomly placed into either of the following
treatment groups: group 1, HA injections with PT (HAPT group); or group 2, PT alone
(PT group).
Interventions
The patients in group 1 received intra-articular glenohumeral joint injections of
HA, 20mg, once per week for 3 consecutive weeks and also participated in a PT program
for 3 months. The patients in group 2 received PT alone.
Main Outcome Measures
Active and passive range of motion (ROM) of the affected shoulder, pain, disability,
and quality of life.
Results
Both groups experienced improvements in terms of pain, disability, and quality of
life after the treatments; furthermore, the active and passive ROM improved linearly
with increasing treatment duration. When the groups were compared, no significant
group effect was found for any of the outcome measurements.
Conclusions
Intra-articular HA injections did not produce added benefits for patients with AC
of the shoulder who were already receiving PT. Thus, the use of intra-articular HA
injections for patients with AC of the shoulder should be carefully assessed to reduce
unnecessary medical expenditures.
Key Words
List of Abbreviations:
AC (adhesive capsulitis), HA (hyaluronic acid), PT (physical therapy), ROM (range of motion), SDQ (Shoulder Disability Questionnaire), SF-36 (Medical Outcomes Study 36-Item Short-Form Health Survey), SPADI (Shoulder Pain and Disability Index)To read this article in full you will need to make a payment
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Article info
Publication history
Published online: February 24, 2012
Footnotes
Supported by the Shin Kong Wu Ho-Su Memorial Hospital (grant no. SKH-8302-99-DR-42).
No commercial party having a direct financial interest in the results of the research supporting this article has or will confer a benefit on the authors or on any organization with which the authors are associated.
Trial Registration No. 95E-049.
In-press corrected proof published online on Feb 24, 2012, at www.archives-pmr.org.
Identification
Copyright
© 2012 American Congress of Rehabilitation Medicine. Published by Elsevier Inc. All rights reserved.
