This paper is only available as a PDF. To read, Please Download here.
Abstract
A 77-year-old man who was undergoing comprehensive rehabilitation for a right subcapital
femoral neck fracture presented with intermittent digital cyanosis of 3 days duration.
He had no other cardiopulmonary signs or symptoms, therefore a diagnosis of Raynaud's
Phenomenon was considered but ruled out because of no prior history of similar episodes
or associated conditions. A ventilation-perfusion (
) scan was obtained and was highly indicative of pulmonary embolus. Dopplers and impedance
plethysmography (IPG) revealed a left lower extremity deep vein thrombosis. Heparinization
resulted in cessation of the cyanotic episodes. Intermittent digital cyanosis as the
sole presentation of pulmonary embolus has not been previously reported in humans.
Pulmonary embolus is notoriously difficult to diagnose based on clinical signs and
symptoms. Intermittent peripheral cyanosis should raise the index of suspicion for
the possibility of pulmonary embolus.

To read this article in full you will need to make a payment
Purchase one-time access:
Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online accessOne-time access price info
- For academic or personal research use, select 'Academic and Personal'
- For corporate R&D use, select 'Corporate R&D Professionals'
Subscribe:
Subscribe to Archives of Physical Medicine and RehabilitationAlready a print subscriber? Claim online access
Already an online subscriber? Sign in
Register: Create an account
Institutional Access: Sign in to ScienceDirect
References
- Evaluation of pulmonary embolism.Radiol Clin N Am. 1985; 23: 391-405
- Diagnosis of pulmonary embolism.Arch Int Med. 1986; 146: 961-967
- Diagnosing pulmonary embolism using clinical findings.Arch Int Med. 1986; 146: 1699-1704
- Recent advances in diagnosis of pulmonary embolism and deep venous thrombosis.Am Rev Resp Dis. 1986; 138: 1046-1047
- Clinical diagnosis of acute massive pulmonary embolism.Lancet. 1969; 1: 271-273
- Massive acute pulmonary embolism. the deceivingly nonspecific manifestations.JAMA. 1972; 220: 843-844
- Pulmonary embolism.Med Clin N Am. 1977; 70: 877-894
- The prevalence of intermittent digital ischaemia (Raynaud's phenomenon) in a general practice.J Royal Coll Gen Pract. 1983; 33: 85-89
- Digital ischemia of the upper extremity: a systematic approach for evaluation and treatment.Plastic and Reconstructive Surgery. 1988; 82: 653-657
- Emboli to the arm.Ann Surg. 1964; 160: 905-909
- Prevalence of Raynaud phenomenon in the general population.J Chron Dis. 1986; 39: 423-427
- Late onset Raynaud's syndrome: diagnostic and therapeutic considerations.Geriatrics. 1988; 43: 59-70
- How to classify Raynaud's phenomenon. long term follow-up study of 73 cases.Am J Med. 1987; 83: 494-498
- Accuracy of the clinical diagnosis of pulmonary embolism.JAMA. 1967; 202: 115-118
- Pulmonary thromboembolism. diagnosis and treatment.JAMA. 1983; 249: 2945-2950
- The clinical features of submassive and massive pulmonary emboli.Am J Med. 1977; 62: 355-360
- Natural history of pulmonary embolism.Prog Cardiovasc Dis. 1975; 17: 259-270
- Importance of shock and cyanosis in pulmonary embolism.Ann Surg. 1967; 165: 528-535
- Unrecognized emboli to the lungs with subsequent cor pulmonale.New Engl J Med. 1953; 249: 919-926
- Diagnosis of pulmonary embolism.J Am Coll Cardiol. 1986; 8: 128B-136B
- Effect of shock upon the initial blood has data in experimental fat embolism.Arch Surg. 1971; 102: 501-502
- Changes in erythrocyte sedimentation rate and C-reactive protein after total hip arthroplasty.Clin Orthop. 1984; 184: 118-120
- Heparin and the ESR [letter].Arch Int Med. 1978; 138: 1864-1865
- Clinical significance of the erythrocyte sedimentation rate in orthopedic surgery.J Bone Joint Surg. 1987; 69-A: 148-151
- Erythrocyte sedimentation rate and C-reactive protein values in patients with total hip arthroplasty.Clin Orthop. 1987; 225: 238-246
Article info
Publication history
Accepted:
December 8,
1993
Received:
August 4,
1993
Identification
Copyright
© 1994 Published by Elsevier Inc.