Archives of Physical Medicine and Rehabilitation
Volume 77, Issue 11 , Pages 1205-1208, November 1996

Hypoxic brain injury: Evaluation by single photon emission computed tomography☆

  • Jon Rupright, DO

      Affiliations

    • Corresponding Author InformationReprint requests to Jon Rupright, DO, Assistant Professor of Physical Medicine and Rehabilitation, University of Missouri Health Sciences Center, Rusk Rehabilitation Center, I Hospital Drive, Columbia, MO 65212.
    • Department of Physical Medicine and Rehabilitation, Rusk Rehabilitation Center, Columbia, MO USA
    • ,
  • Edward A. Woods, MD

      Affiliations

    • Department of Physical Medicine and Rehabilitation, Rusk Rehabilitation Center, Columbia, MO USA
    • ,
  • Amolak Singh, MD

      Affiliations

    • Department of Nuclear Medicine, University of Missouri Health Sciences Center, Columbia, MO USA

Received 15 December 1995; accepted 25 March 1996.

Abstract 

Single photon emission computed tomography (SPECT) with 99mTc-labeled hexamethylpropylene-amine oxime (HMPAO) was used to evaluate cerebral blood flow in 6 patients with hypoxic brain injury (HBI). The SPECT scans were compared with electroencephalograms (EEGs), magnetic resonance imaging (MRI) scans, or computer tomography (CT) scans. The findings on SPECT scans in all 6 patients supported the clinical impression of HBI. SPECT showed decreased perfusion in regions of the brain including the hippocampus, cerebellum white matter, rostral brain stem, the cortex, and occiput. MRI, CT, and EEG provided information that was often not representative of HBI. It was believed that SPECT provided more useful information in the identification of HBI. SPECT imaging with 99mTc HMPAO appears to be a valuable adjunct for evaluation and clinical diagnosis of HBI patients.

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☆ No commercial party having a direct financial interest in the results of the study supporting this article as or will confer a benefit upon the authors or upon any organization with which the authors are associated.

PII: S0003-9993(96)90150-1

Archives of Physical Medicine and Rehabilitation
Volume 77, Issue 11 , Pages 1205-1208, November 1996

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