Archives of Physical Medicine and Rehabilitation
Volume 91, Issue 1 , Pages 30-34 , January 2010

Effect of Intrathecal Baclofen Bolus Injection on Lower Extremity Joint Range of Motion During Gait in Patients With Acquired Brain Injury

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    Joint angle curves for hip (top), knee (middle), and ankle (bottom) joints on the more affected side at baseline (solid bold line) and at 2 (short broken line), 4 (long broken bold line), and 6 (short

    Joint angle curves for hip (top), knee (middle), and ankle (bottom) joints on the more affected side at baseline (solid bold line) and at 2 (short broken line), 4 (long broken bold line), and 6 (short-long broken line) hours after the ITB bolus injection. The corresponding vertical lines indicate toe-off for each time point. ROM significantly improved in the knee (30° to 44°) and ankle (9° to 15°) at 4 hours after the injection. Although there was no significant change in the hip, the overall curve shifted toward normative values. At the same time, the mean Ashworth score decreased from 2.4 to 1.2.

 Supported in part by the National Institute on Disability and Rehabilitation Research (grant nos. H133A020514 and H133A980035), the U.S. Department of Education, Medtronic, Inc, research grants, and the Wilson Research Foundation, Jackson, MS.

 A commercial party having a direct financial interest in the results of the research supporting this article has conferred or will confer a financial benefit on the author or one or more of the authors. Yablon is a consultant for Medtronic Inc, which manufactures intrathecal baclofen pumps.

 Reprints are not available from the author.

 Published online November 13, 2009 at www.archives-pmr.org.

PII: S0003-9993(09)00756-4

doi: 10.1016/j.apmr.2009.08.148

Archives of Physical Medicine and Rehabilitation
Volume 91, Issue 1 , Pages 30-34 , January 2010