Archives of Physical Medicine and Rehabilitation
Volume 90, Issue 9 , Pages 1462-1468 , September 2009

Effect of Baseline Spastic Hemiparesis on Recovery of Upper-Limb Function Following Botulinum Toxin Type A Injections and Postinjection Therapy

Presented to the American Academy of Physical Medicine and Rehabilitation, November 22, 2008, San Diego, CA.

  • Chia-Lin Chang, PhD, PT

      Affiliations

    • Department of Physical Medicine & Rehabilitation, University of Pittsburgh, Pittsburgh, PA
    • ,
  • Michael C. Munin, MD

      Affiliations

    • Department of Physical Medicine & Rehabilitation, University of Pittsburgh, Pittsburgh, PA
    • Corresponding Author InformationReprint requests to Michael C. Munin, MD, Dept of Physical Medicine and Rehabilitation, 3471 Fifth Ave, Ste 201, Kaufman Building, University of Pittsburgh, Pittsburgh, PA, 15213
    • ,
  • Elizabeth R. Skidmore, PhD, OTR/L

      Affiliations

    • Department of Occupational Therapy, University of Pittsburgh, Pittsburgh, PA
    • ,
  • Christian Niyonkuru, MS

      Affiliations

    • Department of Physical Medicine & Rehabilitation, University of Pittsburgh, Pittsburgh, PA
    • ,
  • Lynne M. Huber, BS, OTR/L

      Affiliations

    • University of Pittsburgh Medical Center, Pittsburgh, PA
    • ,
  • Douglas J. Weber, PhD

      Affiliations

    • Department of Physical Medicine & Rehabilitation, University of Pittsburgh, Pittsburgh, PA
    • Department of Bioengineering, University of Pittsburgh, Pittsburgh, PA

  • Image Result

    Experimental protocol time table.

    Experimental protocol time table.

  • Image Result

    Outcome measures for Chedoke-McMaster Assessment Hand-Lower Function and Chedoke-McMaster Assessment Hand-Higher Function groups at baseline (preinjection), 6 weeks, 9 weeks, and 12 weeks postinjectio

    Outcome measures for Chedoke-McMaster Assessment Hand-Lower Function and Chedoke-McMaster Assessment Hand-Higher Function groups at baseline (preinjection), 6 weeks, 9 weeks, and 12 weeks postinjection. MAL-2); Motor Activity Log-5 items (wash hands, dry hands, pick up a phone, operate a door knob, and pick up a glass and take a drink); participant's perception of self-performance in activities of daily living assessed with the MALSR; ARAT; MAS. Abbreviations: CMA-L, Chedoke-McMaster Assessment Hand-Lower Function; CMA-H; Chedoke-McMaster Assessment Hand-Higher Function, MALSR, Motor Activity Log—Self Report; MAL, Motor Activity Log; MAL-28, Motor Activity Log-28.

  • Image Result
    (A) Changes between baseline and 6 weeks after postinjection therapy (B) changes between baseline and 12 weeks postinjection. Abbreviations: CMA-L, Chedoke-McMaster Assessment Hand-Lower Function; CMA

    (A) Changes between baseline and 6 weeks after postinjection therapy (B) changes between baseline and 12 weeks postinjection. Abbreviations: CMA-L, Chedoke-McMaster Assessment Hand-Lower Function; CMA-H; Chedoke-McMaster Assessment Hand-Higher Function, MALSR, Motor Activity Log—Self Report; MAL, Motor Activity Log; MAL-28, Motor Activity Log-28.

 Supported by Allergan Inc; National Institutes of Health Post-Doctoral Training (grant no. T32 HD049307), and National Institutes of Health (grant no. K12 HD055931).

 No commercial party having a direct financial interest in the results of the research supporting this article has or will confer a benefit on the authors or on any organization with which the authors are associated.

PII: S0003-9993(09)00341-4

doi: 10.1016/j.apmr.2009.03.008

Archives of Physical Medicine and Rehabilitation
Volume 90, Issue 9 , Pages 1462-1468 , September 2009

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